{"id":"W2938371712","doi":"10.1134/s0026898419010038","title":"Различия в экспрессии генов титина и небулина в скелетных мышцах крыс, хронически алкоголизированных разными методами","year":2019,"lang":"ru","type":"article","venue":"Молекулярная биология","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"GRi Simulations (Canada)","funders":"","keywords":"Titin; Nebulin; Calpastatin; Calpain; Chemistry; Autolysis (biology); Sarcomere; Biochemistry; Skeletal muscle; Internal medicine; Endocrinology; Molecular biology; Biology; Enzyme; Myocyte","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.001315897,0.001375951,0.001154363,0.0004135782,0.0005705321,0.0003682194,0.001035265,0.002136499,0.005984632],"category_scores_gemma":[0.0003635571,0.001395324,0.001100164,0.0007980764,0.0004986834,0.00006921089,0.0007767794,0.001141848,0.006825204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002883327,"about_ca_system_score_gemma":0.0008576469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002473578,"about_ca_topic_score_gemma":0.000238632,"domain_scores_codex":[0.9923116,0.0005742244,0.001551468,0.002519228,0.001247336,0.001796172],"domain_scores_gemma":[0.9948832,0.0001382612,0.0008054246,0.002635808,0.0006727864,0.0008645072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002700285,0.002055333,0.02877811,0.001670021,0.00179424,0.0001205462,0.0006261275,0.001186723,0.7209646,0.00958146,0.1799251,0.05059743],"study_design_scores_gemma":[0.005033214,0.001805906,0.01961793,0.0004465634,0.0003987077,0.0002057511,0.0009172392,0.001750701,0.09602582,0.0006641788,0.8704641,0.002669921],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8655267,0.01064196,0.002318277,0.004037295,0.007499708,0.003978716,0.0005193185,0.0004132078,0.1050648],"genre_scores_gemma":[0.857096,0.001039093,0.0004544161,0.002303668,0.002906468,0.0001203941,0.001485645,0.0002741957,0.1343201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6905389,"threshold_uncertainty_score":0.9998991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003423786402207396,"score_gpt":0.2047435143061368,"score_spread":0.2013197279039294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}