{"id":"W2938589827","doi":"10.1016/s1470-2045(19)30082-8","title":"Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial","year":2019,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":813,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"Janssen Research and Development","keywords":"Abiraterone acetate; Prostate cancer; Medicine; Prednisone; Internal medicine; Oncology; Androgen deprivation therapy; Urology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001468694,0.001236225,0.002021468,0.000389805,0.0003551341,0.0009629949,0.0005290363,0.0008421415,0.003742973],"category_scores_gemma":[0.001601167,0.000409117,0.002235223,0.0004374228,0.001023265,0.0007376166,0.0003984352,0.00220603,0.0005929218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006122254,"about_ca_system_score_gemma":0.001138711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001948977,"about_ca_topic_score_gemma":0.00528966,"domain_scores_codex":[0.9994543,0.0003291426,0.0000338363,0.00006898664,0.00003955627,0.00007410247],"domain_scores_gemma":[0.9990938,0.0002809541,0.0002205213,0.00008350064,0.00003868548,0.0002825124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9792814,0.001270543,0.0006878549,0.0004820733,0.001102096,0.00002597704,0.00006292565,0.0004746834,0.001298099,0.00006537744,0.0004347101,0.01481415],"study_design_scores_gemma":[0.9536874,0.04186127,0.002707129,0.00003406293,0.0006007713,0.00004599296,0.00003226268,0.0002341076,0.0001705799,0.0001673301,0.0004448259,0.00001431069],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983717,0.01139455,0.0004578411,0.000509055,0.0004484061,0.000925603,0.0006950522,0.0001115163,0.001741001],"genre_scores_gemma":[0.9898416,0.005156499,0.0006561044,0.0005679188,0.0003439136,0.0007355726,0.0006968052,0.00002015543,0.001981392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003742973,"threshold_uncertainty_score":0.01252145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06476036434540433,"score_gpt":0.3773706945959527,"score_spread":0.3126103302505484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}