{"id":"W2938872819","doi":"10.1016/bs.mie.2019.03.021","title":"Prenylated FMN: Biosynthesis, purification, and Fdc1 activation","year":2019,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Biochemical and biochemical processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Ontario Genomics Institute; Genome Canada","keywords":"Flavin mononucleotide; Prenyltransferase; Flavin group; Prenylation; Biosynthesis; Cofactor; Biochemistry; Enzyme; Chemistry; Biotransformation; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.003355538,0.0005642193,0.0008795976,0.0004345624,0.00007467014,0.00002550038,0.0006334973,0.001778816,0.0001871566],"category_scores_gemma":[0.003743852,0.0005269017,0.000131741,0.0007023798,0.000615062,0.00001951595,0.0003636967,0.0008751126,0.00002851246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008331898,"about_ca_system_score_gemma":0.0001074127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007192056,"about_ca_topic_score_gemma":0.00004431978,"domain_scores_codex":[0.9932867,0.003111157,0.0009607847,0.001646257,0.0001629844,0.000832119],"domain_scores_gemma":[0.9969465,0.001499446,0.0003406014,0.0009063971,0.0001426097,0.0001644447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005185355,0.0003608288,0.006765637,0.00009750362,0.00005673892,0.000006342778,0.00008086357,0.00002304485,0.9563315,0.0009069344,0.0003168793,0.03453521],"study_design_scores_gemma":[0.001253337,0.0006656832,0.03607273,0.00006539518,0.00002332319,0.00008373058,0.00008548377,0.00006864376,0.9409909,0.008854622,0.01123351,0.0006026446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773001,0.002018259,0.01602474,0.001168268,0.0005625074,0.0006951886,0.00001427548,0.00006202135,0.002154612],"genre_scores_gemma":[0.5701265,0.0004067261,0.4271509,0.001357478,0.0001524516,0.0001365908,0.0001029156,0.00005732281,0.0005090238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4111262,"threshold_uncertainty_score":0.9997182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02471384269625386,"score_gpt":0.3681638810528107,"score_spread":0.3434500383565569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}