{"id":"W2938966525","doi":"10.1016/j.joca.2019.02.671","title":"Circulating microRNA signatures identified in early versus late knee osteoarthritis","year":2019,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Krembil Foundation","funders":"","keywords":"Osteoarthritis; microRNA; Medicine; Biomarker; Biobank; Oncology; Internal medicine; Bioinformatics; Synovial fluid; Disease; Pathology; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039605,0.000251165,0.0005447143,0.0009149387,0.0002563125,0.001074591,0.0001842146,0.0005972363,0.002080589],"category_scores_gemma":[0.001126817,0.0002671176,0.0002653089,0.0006311818,0.0002496506,0.0003004021,0.0002930044,0.0004814455,0.0004430187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001511509,"about_ca_system_score_gemma":0.0001624491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003160193,"about_ca_topic_score_gemma":0.000589724,"domain_scores_codex":[0.9996777,0.00005849358,0.00003752861,0.00008725555,0.0000616771,0.0000773807],"domain_scores_gemma":[0.9993607,0.0001817034,0.0002496466,0.00003342895,0.00006581507,0.0001087178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007782714,0.0001770392,0.5452208,0.0002422601,0.0002998025,0.00141194,0.0004633724,0.000180306,0.418488,0.0005522901,0.0006591652,0.02452235],"study_design_scores_gemma":[0.0001036759,0.0008158825,0.9698613,0.0000389002,0.0002491317,0.003670479,0.0004949456,0.001313844,0.02071329,0.0005824692,0.002119474,0.00003648499],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964296,0.001393157,0.0007442367,0.00005705578,0.00004143682,0.00001018231,0.0004368405,0.00002245029,0.0008650209],"genre_scores_gemma":[0.9976432,0.0002495122,0.0007206423,0.00008972825,0.00005044842,0.00002036969,0.0003318428,0.00001529839,0.0008790057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002080589,"threshold_uncertainty_score":0.006960273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00664906739985498,"score_gpt":0.2328181809543762,"score_spread":0.2261691135545212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}