{"id":"W2939056740","doi":"10.1007/s00253-019-09821-z","title":"Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134","year":2019,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Science Foundation of Shandong Province; National Natural Science Foundation of China; Griffith University","keywords":"Bipolaris; Gene cluster; Genome; Polyketide; Fungus; Gene; Ascomycota; Biology; Chemistry; Magnaporthe grisea; Stereochemistry; Microbiology; Biochemistry; Biosynthesis; Botany; Oryza sativa","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001620063,0.0005804742,0.0006473902,0.00108949,0.0003518821,0.0007471343,0.0003082987,0.000450204,0.0008392992],"category_scores_gemma":[0.0003632043,0.000202926,0.0006368764,0.001110575,0.0002238089,0.0002683536,0.0003901736,0.0004821426,0.0005250533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002353817,"about_ca_system_score_gemma":0.0004756378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002034592,"about_ca_topic_score_gemma":0.003727038,"domain_scores_codex":[0.9998237,0.0000128059,0.00001177192,0.00006457175,0.00006684606,0.00002027786],"domain_scores_gemma":[0.9997616,0.00006052201,0.00007339804,0.00001974253,0.0000513268,0.00003334886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003181356,0.00005333206,0.003537891,0.0002351373,0.00005810767,0.0002517992,0.00008041051,0.0003030395,0.9863282,0.00006135666,0.0002449655,0.008527553],"study_design_scores_gemma":[0.0001260257,0.0008024389,0.2562411,0.0001268377,0.001073347,0.003927168,0.000937795,0.009824124,0.6959472,0.0005633353,0.03029059,0.0001400072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9503416,0.0029193,0.01175944,0.000309879,0.000056473,0.0001004341,0.03152826,0.0006592563,0.002325403],"genre_scores_gemma":[0.9233804,0.001466205,0.02278093,0.0001786818,0.00003292046,0.00005907847,0.04887563,0.0002480133,0.002978234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002034592,"threshold_uncertainty_score":0.004045546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006235628153790338,"score_gpt":0.1951069814687138,"score_spread":0.1888713533149235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}