{"id":"W2939056740","doi":"10.1007/s00253-019-09821-z","title":"Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134","year":2019,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Science Foundation of Shandong Province; National Natural Science Foundation of China; Griffith University","keywords":"Bipolaris; Gene cluster; Genome; Polyketide; Fungus; Gene; Ascomycota; Biology; Chemistry; Magnaporthe grisea; Stereochemistry; Microbiology; Biochemistry; Biosynthesis; Botany; Oryza sativa","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002130654,0.0002447382,0.0005733621,0.0001249482,0.000106249,0.00001133412,0.0001255441,0.0007281929,0.00009862104],"category_scores_gemma":[0.00003113637,0.0001566846,0.0000409655,0.0001699844,0.0009145466,0.00002062824,0.0001595986,0.0003132379,0.000005758293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009318737,"about_ca_system_score_gemma":0.00003736459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006439436,"about_ca_topic_score_gemma":0.00003698846,"domain_scores_codex":[0.9987822,0.0000411522,0.0002905068,0.000560464,0.0000275157,0.0002981511],"domain_scores_gemma":[0.9993207,0.0001282834,0.0001660232,0.000313529,0.00003154841,0.00003988339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005545328,0.00004329008,0.003836554,0.0000645044,0.0001217032,0.000005405868,0.00008914148,5.86473e-8,0.9848812,0.0001641254,0.00002109998,0.01021837],"study_design_scores_gemma":[0.001626414,0.0003926468,0.03934471,0.0000411995,0.0001569584,0.0001792845,0.0001806713,0.000004096323,0.9476777,0.0000472251,0.0101429,0.0002062188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908776,0.00454645,0.000007697714,0.003441216,0.0001500022,0.0005195365,0.0003791206,0.0000578192,0.00002054091],"genre_scores_gemma":[0.9975749,0.0007933349,0.0009360728,0.000353389,0.00009948584,0.00000165106,0.0001947257,0.00001651834,0.00002989931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03720354,"threshold_uncertainty_score":0.6389411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006235628153790338,"score_gpt":0.1951069814687138,"score_spread":0.1888713533149235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}