{"id":"W2939558853","doi":"10.1016/j.eururo.2019.03.011","title":"RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression","year":2019,"lang":"en","type":"article","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute; Prostate Cancer UK; Prostate Cancer Canada","keywords":"RNA splicing; Cancer research; Biology; Transcriptome; Alternative splicing; Demethylase; Prostate cancer; Epigenetics; Long non-coding RNA; RNA; Gene; Cell biology; Cancer; Gene expression; Exon; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000159235,0.0001207006,0.0002364052,0.00008227106,0.00005282754,0.000007541485,0.0001659236,0.00001369935,0.0001096321],"category_scores_gemma":[0.00006056636,0.00006791964,0.00006423538,0.0002417749,0.00009152919,0.00002242097,0.0002404385,0.000199566,0.0001413644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003956546,"about_ca_system_score_gemma":0.00008123211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002767665,"about_ca_topic_score_gemma":0.000004595788,"domain_scores_codex":[0.9988022,0.0001957087,0.0002090065,0.0002726542,0.0001732062,0.0003472029],"domain_scores_gemma":[0.9992928,0.00004698757,0.00007937619,0.0003794097,0.0001113919,0.00009002729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00188927,0.00013666,0.3502886,0.000103897,0.0001209193,0.0002453512,0.0002949266,0.0001303923,0.6206588,0.00009729721,0.00294936,0.02308462],"study_design_scores_gemma":[0.005852574,0.00210205,0.5694937,0.0001690637,0.0001301341,0.00009724649,0.00003003595,0.0001727201,0.312207,0.00003984417,0.109556,0.0001496144],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9716717,0.001341742,0.000007995673,0.01929871,0.0003878401,0.001186143,0.00001643974,0.00003365257,0.00605581],"genre_scores_gemma":[0.9906847,0.0002686241,0.00003980367,0.002010437,0.00009257051,0.00002528415,0.000009078645,0.00003507094,0.006834457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3084518,"threshold_uncertainty_score":0.2769682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01344504468149999,"score_gpt":0.3097389980184727,"score_spread":0.2962939533369727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}