{"id":"W2939607680","doi":"10.1111/his.13875","title":"Colorectal large‐cell neuroendocrine carcinoma with lymphoid stroma: further evidence confirming a unique subtype associated with MLH1/PMS2 loss, <i>BRAF</i> mutation, Epstein–Barr virus negativity, and the possibility of a better prognosis","year":2019,"lang":"en","type":"article","venue":"Histopathology","topic":"Neuroendocrine Tumor Research Advances","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Synaptophysin; Pathology; Chromogranin A; Biology; Carcinoma; Adenocarcinoma; Immunohistochemistry; Medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001429505,0.0002970477,0.0002329054,0.0005017043,0.0003709018,0.0003916645,0.0002419427,0.0004424428,0.001753055],"category_scores_gemma":[0.0006294043,0.0001713111,0.000193148,0.0004154211,0.0002642827,0.000176921,0.0003275709,0.0002295724,0.0005920019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002173429,"about_ca_system_score_gemma":0.0001981485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001353833,"about_ca_topic_score_gemma":0.002248878,"domain_scores_codex":[0.999894,0.00001070759,0.00001308337,0.0000265242,0.00001958918,0.00003602513],"domain_scores_gemma":[0.9995847,0.0000748403,0.00008887056,0.00006005551,0.00004987654,0.000141565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005472613,0.00008919784,0.5671253,0.0001110221,0.00004628688,0.3833857,0.0002949752,0.0001180016,0.04111961,0.0001213705,0.0003748387,0.006666449],"study_design_scores_gemma":[0.00002747244,0.0001873105,0.245507,0.000007436978,0.00002980107,0.7496284,0.0002246492,0.0003781103,0.002652605,0.00005573081,0.001292823,0.000008608667],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985589,0.0002841614,0.0001968464,0.00003201994,0.000007279986,0.000009264626,0.00005879653,0.00001028305,0.0008423757],"genre_scores_gemma":[0.9994759,0.00007095472,0.0001325619,0.00001294761,0.0000187921,0.000002657925,0.00007889104,0.000002540679,0.0002046674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001753055,"threshold_uncertainty_score":0.005864561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0112912852852827,"score_gpt":0.2553110490103591,"score_spread":0.2440197637250764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}