{"id":"W2939607680","doi":"10.1111/his.13875","title":"Colorectal large‐cell neuroendocrine carcinoma with lymphoid stroma: further evidence confirming a unique subtype associated with MLH1/PMS2 loss, <i>BRAF</i> mutation, Epstein–Barr virus negativity, and the possibility of a better prognosis","year":2019,"lang":"en","type":"article","venue":"Histopathology","topic":"Neuroendocrine Tumor Research Advances","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Synaptophysin; Pathology; Chromogranin A; Biology; Carcinoma; Adenocarcinoma; Immunohistochemistry; Medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004768095,0.0003397912,0.0008172605,0.000151492,0.0001256169,0.00002338137,0.0002245735,0.00002609384,0.00007829365],"category_scores_gemma":[0.0007107751,0.000217146,0.00008040138,0.0004338796,0.001362401,0.0002353411,0.000167554,0.0004792565,0.00001075644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001490907,"about_ca_system_score_gemma":0.0004033197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004251018,"about_ca_topic_score_gemma":0.0008914678,"domain_scores_codex":[0.9967119,0.0009489765,0.0004463924,0.000732325,0.0005155889,0.0006448073],"domain_scores_gemma":[0.9973781,0.001040148,0.0004309924,0.0005402052,0.0004488543,0.0001617458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005409976,0.0004975562,0.9481374,0.0002684789,0.00002361101,0.008350597,0.0006334246,0.000005584974,0.03647127,0.00008386347,0.00005075301,0.00006745798],"study_design_scores_gemma":[0.01815401,0.008107466,0.9022286,0.0002843302,0.0002949083,0.01754251,0.0003207597,0.0002947487,0.05204841,0.000147388,0.0002327282,0.0003441215],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941323,0.0007133078,0.00003231234,0.002564413,0.00006526284,0.002068692,0.00004224977,0.00007334531,0.0003080875],"genre_scores_gemma":[0.998422,0.00003817379,0.0002627974,0.0006071433,0.00002706227,0.0001776256,0.00001860314,0.0000598745,0.0003866752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04590881,"threshold_uncertainty_score":0.8854958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0112912852852827,"score_gpt":0.2553110490103591,"score_spread":0.2440197637250764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}