{"id":"W2939620966","doi":"10.2298/abs190404027t","title":"Enrichment of Cxcl12 promoter with TET2: A possible link between promoter demethylation and enhanced gene expression in the absence of PARP-1","year":2019,"lang":"en","type":"article","venue":"Archives of Biological Sciences","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja; Alexander von Humboldt-Stiftung","keywords":"Biology; Promoter; DNA demethylation; Molecular biology; Poly ADP ribose polymerase; DNA methylation; Gene expression; Demethylation; CpG site; Gene; Regulation of gene expression; Transcription (linguistics); Cell biology; Genetics; Polymerase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001775276,0.0002606659,0.0002573176,0.0001928903,0.0001208775,0.0002263947,0.0002504299,0.0002867209,0.002086451],"category_scores_gemma":[0.0002640253,0.0002050372,0.0002080243,0.0001311388,0.0002031481,0.0001891968,0.0002196845,0.000412854,0.0003478458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001498204,"about_ca_system_score_gemma":0.00009882405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004436983,"about_ca_topic_score_gemma":0.0004551416,"domain_scores_codex":[0.9998305,0.00003590554,0.00001133314,0.00005283488,0.00003284063,0.00003647205],"domain_scores_gemma":[0.9997756,0.0000528833,0.00008439242,0.00002823605,0.00002821446,0.00003072946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008622351,0.0000102536,0.000543555,0.00004161448,0.000006466079,0.00008290341,0.00001890371,0.00004276853,0.9981055,0.0000824278,0.0000259153,0.0009534366],"study_design_scores_gemma":[0.00001397363,0.000167502,0.01979563,0.0000106095,0.00002262087,0.000592953,0.00003514536,0.0009533317,0.976034,0.0001084099,0.00226022,0.00000572958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98562,0.002889797,0.009817061,0.0001810778,0.00004067171,0.00002382801,0.0003563983,0.0001243307,0.0009469393],"genre_scores_gemma":[0.993583,0.000672001,0.002792563,0.0001008396,0.00001254938,0.00002706674,0.0007145022,0.0000253059,0.002072176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002086451,"threshold_uncertainty_score":0.006979883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02128659322566102,"score_gpt":0.2755152631365836,"score_spread":0.2542286699109226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}