{"id":"W2939627719","doi":"10.1093/sleep/zsz067.471","title":"0473 Alendronate is Associated With a Significantly Higher Odds of Obstructive Sleep Apnea (OSA): Results from the US FDA Adverse Events Reporting System (FAERS)","year":2019,"lang":"en","type":"article","venue":"SLEEP","topic":"Bone and Joint Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Taiwan University; National Taiwan University Hospital Yunlin Branch; National Taiwan University Hospital","keywords":"Medicine; MedDRA; Odds ratio; Obstructive sleep apnea; Internal medicine; Adverse Event Reporting System; Adverse effect; Bisphosphonate; Confidence interval; Polysomnography; Osteoporosis; Pharmacovigilance; Apnea","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003993594,0.0002964558,0.0004571237,0.002144689,0.0003295562,0.001082665,0.0003942622,0.0004408901,0.002881557],"category_scores_gemma":[0.0161826,0.0001986903,0.002155005,0.004643887,0.0002268986,0.0006385451,0.0006279234,0.0006067505,0.0006383702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005202605,"about_ca_system_score_gemma":0.0009063641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009509766,"about_ca_topic_score_gemma":0.008814658,"domain_scores_codex":[0.991904,0.001498385,0.002685127,0.001142506,0.002422935,0.0003470888],"domain_scores_gemma":[0.9774737,0.005362891,0.01372363,0.0008107827,0.0021447,0.0004842928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003073629,0.00002755392,0.9933969,0.0001649802,0.0004805762,0.00008074963,0.00006413209,0.00005777977,0.0001756212,0.00003359456,0.0009642887,0.004246378],"study_design_scores_gemma":[0.00001563141,0.00007528363,0.9966474,0.00008842766,0.0003820193,0.0003782462,0.0001186285,0.0003243158,0.0001956791,0.00003845277,0.001725368,0.00001055582],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9666727,0.007077874,0.0006107118,0.0006489081,0.00006374623,0.00009027012,0.02144535,0.00005799651,0.003332499],"genre_scores_gemma":[0.9844358,0.002169262,0.0005740396,0.0003896876,0.00009618834,0.00006913355,0.01153757,0.00002891667,0.0006993604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009509766,"threshold_uncertainty_score":0.02112043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01593822769047985,"score_gpt":0.2371356126164872,"score_spread":0.2211973849260073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}