{"id":"W2939627719","doi":"10.1093/sleep/zsz067.471","title":"0473 Alendronate is Associated With a Significantly Higher Odds of Obstructive Sleep Apnea (OSA): Results from the US FDA Adverse Events Reporting System (FAERS)","year":2019,"lang":"en","type":"article","venue":"SLEEP","topic":"Bone and Joint Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Taiwan University; National Taiwan University Hospital Yunlin Branch; National Taiwan University Hospital","keywords":"Medicine; MedDRA; Odds ratio; Obstructive sleep apnea; Internal medicine; Adverse Event Reporting System; Adverse effect; Bisphosphonate; Confidence interval; Polysomnography; Osteoporosis; Pharmacovigilance; Apnea","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004537596,0.0002705053,0.0006848198,0.00006201836,0.00008919573,0.00000781739,0.000152286,0.0001465247,0.0002452666],"category_scores_gemma":[0.0004356245,0.0001762615,0.0002338812,0.000311172,0.0000875082,0.0001245988,0.0000679744,0.0002712163,0.0001298648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001700489,"about_ca_system_score_gemma":0.0000970921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001334874,"about_ca_topic_score_gemma":0.00004992094,"domain_scores_codex":[0.9971468,0.0001399214,0.001096495,0.0005384547,0.0006950947,0.0003832291],"domain_scores_gemma":[0.9967172,0.0002344642,0.001831385,0.0007649777,0.000286189,0.0001657836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009072045,0.0009133749,0.9578034,0.0005126416,0.005296984,0.001585274,0.007152712,0.0003133343,0.009129354,0.0002182765,0.002241743,0.005760895],"study_design_scores_gemma":[0.00856743,0.0004663464,0.9779268,0.0014214,0.001419776,0.00003683973,0.004271879,0.001260025,0.003622504,0.00005536833,0.000563768,0.0003878796],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910499,0.0001366144,0.00001513888,0.0003829306,0.0004523373,0.000786999,0.0005069903,0.0001080075,0.006561087],"genre_scores_gemma":[0.9975312,0.000003469465,0.00009955026,0.0003473336,0.0001245082,0.0000211009,0.0002478031,0.0000471616,0.001577882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02012342,"threshold_uncertainty_score":0.7187734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01593822769047985,"score_gpt":0.2371356126164872,"score_spread":0.2211973849260073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}