{"id":"W2939645851","doi":"10.1096/fasebj.2018.32.1_supplement.533.112","title":"Dietary Glycine Supplementation Extends Lifespan of Genetically Heterogeneous Mice","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Biochemical effects in animals","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"National Institute on Aging","keywords":"Glycine; Methionine; Senescence; Endogeny; Biology; Endocrinology; Epigenetics; Internal medicine; Amino acid; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004069516,0.0001094505,0.0001977663,0.00005107675,0.00009364575,0.0000137627,0.0001628753,0.00005691627,0.0009372141],"category_scores_gemma":[0.0001351243,0.00006720587,0.0001067888,0.0001082692,0.0002853727,0.00002707689,0.00005298567,0.0002420073,0.00004569562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000356759,"about_ca_system_score_gemma":0.00005508392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000813666,"about_ca_topic_score_gemma":0.000002781307,"domain_scores_codex":[0.9989139,0.00009192184,0.0003355619,0.0001154566,0.0003228779,0.0002203238],"domain_scores_gemma":[0.9992132,0.00009923756,0.0001416729,0.0002104249,0.0001782373,0.0001572713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006806173,0.00008927975,0.0008447309,0.00002611321,0.0001034094,0.00003089992,0.000168694,0.000002581441,0.9875127,0.00001602448,0.002664004,0.007860961],"study_design_scores_gemma":[0.001194987,0.002191624,0.005104259,0.00008789819,0.000193086,0.001717621,0.0000585674,0.0003736018,0.9884282,0.0001952032,0.0003826388,0.00007227575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955519,0.0004502856,0.0004139168,0.001999306,0.0001913223,0.0001547772,0.000009838083,0.00001358057,0.001215058],"genre_scores_gemma":[0.9933252,0.0001061731,0.004023487,0.001249622,0.001077731,0.000002172258,0.000008632041,0.000016501,0.0001904604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007788686,"threshold_uncertainty_score":0.999976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02257981822636971,"score_gpt":0.3093240003911036,"score_spread":0.2867441821647339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}