{"id":"W2940324041","doi":"10.1016/j.neo.2019.03.009","title":"Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non–Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion","year":2019,"lang":"en","type":"article","venue":"Neoplasia","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; Ontario Institute for Cancer Research; University Health Network; Princess Margaret Cancer Centre","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Cancer-Associated Fibroblasts; Desmoplasia; Stromal cell; Tumor microenvironment; Biology; Cancer research; Lung cancer; Cancer; Transcriptome; Tumor progression; Cancer cell; Cell; Pathology; Stroma; Immunohistochemistry; Medicine; Immunology; Gene expression; Gene; Tumor cells; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001310381,0.0001854931,0.0006110184,0.000121107,0.000026709,0.000006725442,0.00009227932,0.000145852,0.0002558154],"category_scores_gemma":[0.00002858874,0.0001801332,0.0001543592,0.0002575852,0.00001780748,0.00008838544,0.00004110674,0.0001068353,0.000003933648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000242888,"about_ca_system_score_gemma":0.0002437096,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01595777,"about_ca_topic_score_gemma":0.007064878,"domain_scores_codex":[0.9985873,0.00004555587,0.0005736498,0.0003284531,0.0002116363,0.0002534029],"domain_scores_gemma":[0.9988627,0.00008505776,0.0004653546,0.00031946,0.00017522,0.00009215828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001957047,0.0001654903,0.5105762,0.0004177286,0.00001255833,0.000001145165,0.000679205,0.00003009319,0.4874754,0.000003687717,0.00005689785,0.0003858013],"study_design_scores_gemma":[0.003019229,0.000228199,0.753477,0.0003061127,0.0001925859,4.92022e-7,0.0001449206,0.001487842,0.2409173,0.00001560137,0.00009037322,0.0001203023],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963916,0.0003550235,0.000117697,0.00004531951,0.0002348268,0.00136955,0.0008239621,0.0000125593,0.0006494618],"genre_scores_gemma":[0.9972419,0.00004023391,0.0005388397,0.00003969462,0.00007019474,0.00008032061,0.001040592,0.00004006276,0.0009082098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2465581,"threshold_uncertainty_score":0.990595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01872134430195035,"score_gpt":0.251791035530689,"score_spread":0.2330696912287387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}