{"id":"W2940324041","doi":"10.1016/j.neo.2019.03.009","title":"Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non–Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion","year":2019,"lang":"en","type":"article","venue":"Neoplasia","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; Ontario Institute for Cancer Research; University Health Network; Princess Margaret Cancer Centre","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Cancer-Associated Fibroblasts; Desmoplasia; Stromal cell; Tumor microenvironment; Biology; Cancer research; Lung cancer; Cancer; Transcriptome; Tumor progression; Cancer cell; Cell; Pathology; Stroma; Immunohistochemistry; Medicine; Immunology; Gene expression; Gene; Tumor cells; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007137789,0.0001510722,0.0001557897,0.0003674273,0.0001958134,0.0001931668,0.00005094926,0.0001239052,0.0006697011],"category_scores_gemma":[0.0001287629,0.00006570374,0.0002087021,0.0002393014,0.00009590815,0.00009842951,0.0001367048,0.0001553477,0.0001656295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007351909,"about_ca_system_score_gemma":0.0001092484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006225835,"about_ca_topic_score_gemma":0.001382573,"domain_scores_codex":[0.9999292,0.000006031028,0.000008497336,0.00001759155,0.00002187882,0.00001681106],"domain_scores_gemma":[0.9999272,0.00001605854,0.00001634688,0.000006462774,0.00001578255,0.00001823627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001483109,0.00001300045,0.01199227,0.00003289654,0.00000939957,0.0001460844,0.00005383481,0.00002361324,0.9859807,0.00001713927,0.00002125799,0.001561381],"study_design_scores_gemma":[0.00001867044,0.0003987072,0.6934337,0.00001657872,0.00007720009,0.002859118,0.0005973203,0.001545771,0.2987452,0.00009299738,0.002202449,0.00001231166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982784,0.000389341,0.000479336,0.00001822546,0.000003902428,0.00001256865,0.0004664672,0.000007006112,0.0003447286],"genre_scores_gemma":[0.9965229,0.0003368726,0.000976251,0.00002425921,0.000006051047,0.00003407282,0.001357834,0.00000340589,0.0007383801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006697011,"threshold_uncertainty_score":0.0022403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01872134430195035,"score_gpt":0.251791035530689,"score_spread":0.2330696912287387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}