{"id":"W2940661476","doi":"10.1002/2211-5463.12644","title":"Structural insights into interactions between viral suppressor of <scp>RNA</scp> silencing protein p19 mutants and small <scp>RNA</scp>s","year":2019,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Institute of General Medical Sciences","keywords":"RNA; Small interfering RNA; RNA silencing; Trans-acting siRNA; Gene silencing; RNA-induced transcriptional silencing; Biology; RNA-induced silencing complex; Small RNA; RNA interference; Protein Data Bank (RCSB PDB); Cell biology; Genetics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001141654,0.0003939478,0.0002719572,0.0001665694,0.0002928693,0.0003240943,0.0004999557,0.0003569308,0.001368732],"category_scores_gemma":[0.0001755993,0.0001624525,0.0002899432,0.000185494,0.0002565188,0.0002502855,0.0002014564,0.0006724031,0.0003306369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009002253,"about_ca_system_score_gemma":0.0004127983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003770218,"about_ca_topic_score_gemma":0.003970442,"domain_scores_codex":[0.9999063,0.0000136473,0.000006066238,0.00001583394,0.00004204107,0.00001609695],"domain_scores_gemma":[0.9999014,0.00002641018,0.00002865934,0.000005572918,0.000009385282,0.00002854364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004578434,0.0001333407,0.001504589,0.0001117928,0.00006603367,0.001371911,0.00009133876,0.003479574,0.9887913,0.0009059776,0.0006259773,0.00246029],"study_design_scores_gemma":[0.0002439701,0.000469709,0.01745031,0.00002793036,0.0001442365,0.002228925,0.0002793652,0.0464788,0.9199339,0.0006949917,0.01199923,0.00004874003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964654,0.0006838675,0.001166568,0.0001942781,0.00002002502,0.00001142607,0.000359774,0.00007620596,0.001022374],"genre_scores_gemma":[0.994976,0.000525192,0.002476997,0.000074929,0.000006553146,0.00001062233,0.001006591,0.00002798832,0.0008951214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003770218,"threshold_uncertainty_score":0.007496595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01892043508817314,"score_gpt":0.2651697356294259,"score_spread":0.2462493005412527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}