{"id":"W2941020419","doi":"10.1093/neuonc/noz036.008","title":"ATRT-09. INTEGRATIVE ANALYSES OF GENE REGULATORY LANDSCAPES REVEAL RHABDOID TUMOR SUBGROUPS WITH POSSIBLE IMMUNE MODULATION THROUGH EPIGENETIC DYSREGULATION","year":2019,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Tumors and Oncological Cases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre","funders":"","keywords":"Epigenetics; Immune system; Gene; Immune dysregulation; Biology; Epigenesis; Psychology; DNA methylation; Neuroscience; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004476902,0.0003745243,0.0007318705,0.0006714554,0.0004184718,0.0007608141,0.0006354756,0.0003870327,0.004818795],"category_scores_gemma":[0.0002799277,0.0002998046,0.0009667063,0.0007583805,0.0002227479,0.0001926936,0.0007113768,0.0009761508,0.001736507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000378337,"about_ca_system_score_gemma":0.0004770988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001670767,"about_ca_topic_score_gemma":0.004383625,"domain_scores_codex":[0.9995556,0.00003072745,0.0000229336,0.0001994245,0.0001250439,0.00006629998],"domain_scores_gemma":[0.9998165,0.00003410676,0.00005426537,0.00002863014,0.0000203192,0.00004633173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001665631,0.0001600117,0.03906134,0.000892507,0.0004991941,0.0007305795,0.000398787,0.00291466,0.8949888,0.001880753,0.01073485,0.0460728],"study_design_scores_gemma":[0.0006173172,0.001755364,0.437557,0.0002018092,0.001531664,0.006292394,0.0006605671,0.03144591,0.3363333,0.003124464,0.180314,0.0001662528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8474315,0.003498082,0.02436915,0.0004167513,0.0001791839,0.0002558716,0.1089605,0.00345627,0.01143277],"genre_scores_gemma":[0.7699585,0.001721797,0.03430462,0.0007444115,0.00005023831,0.0005356592,0.1805094,0.001782504,0.01039286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004818795,"threshold_uncertainty_score":0.01612049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02843902868688611,"score_gpt":0.3153083811375602,"score_spread":0.2868693524506741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}