{"id":"W2941122851","doi":"10.3389/fimmu.2019.00926","title":"PACAP Is Lethal to Flavobacterium psychrophilum Through Either Direct Membrane Permeabilization or Indirectly, by Priming the Immune Response in Rainbow Trout Macrophages","year":2019,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Microbiology; Antimicrobial peptides; Pathogen; Flavobacterium; Rainbow trout; Antimicrobial; Immune system; Bacteria; Immunology; Fish <Actinopterygii>","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000140819,0.0002939894,0.000222747,0.0001069889,0.0001361735,0.0001749387,0.000132597,0.0002698172,0.0009690935],"category_scores_gemma":[0.0001036159,0.0001259641,0.0002841924,0.00008281907,0.0002076129,0.0001580907,0.0002680276,0.0004616173,0.0002652498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002025624,"about_ca_system_score_gemma":0.0002357334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001583671,"about_ca_topic_score_gemma":0.001806374,"domain_scores_codex":[0.9998319,0.00002507487,0.00001975626,0.00002885486,0.00004170089,0.0000526359],"domain_scores_gemma":[0.9999303,0.00001204511,0.00001996765,0.000008705186,0.00001220193,0.00001682454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009623783,0.000008653998,0.000161323,0.00002003626,0.000001601134,0.00004962902,0.00001663019,0.00002046598,0.9994478,0.00001493008,0.00001530546,0.0001474192],"study_design_scores_gemma":[0.00002278771,0.001327395,0.02322937,0.00001180683,0.00001725084,0.0003514642,0.0001800076,0.0005618792,0.9730822,0.00003419532,0.001171499,0.00001022548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997948,0.0004192435,0.0004592881,0.00007444555,0.00001914115,0.00002061148,0.0002819186,0.00001877432,0.00075862],"genre_scores_gemma":[0.9963011,0.0003627607,0.0007963792,0.00008137101,0.00001076177,0.00004954487,0.0004632304,0.000007286441,0.001927485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001583671,"threshold_uncertainty_score":0.003241897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01579485114549204,"score_gpt":0.2596813925307421,"score_spread":0.24388654138525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}