{"id":"W2941307471","doi":"10.4049/jimmunol.1801632","title":"The Immune Deficiency Pathway Regulates Metabolic Homeostasis in <i>Drosophila</i>","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary; University of Alberta","funders":"University of Alberta; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Technology Futures","keywords":"Biology; Drosophila melanogaster; Immune system; Metabolic pathway; Homeostasis; Immunity; Mutant; Cell biology; Regulator; Signal transduction; Glucose homeostasis; Insulin resistance; Genetics; Insulin; Gene; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.003614232,0.0002769529,0.0006744968,0.0002869709,0.0003822812,0.00002830356,0.001581158,0.0003056261,0.0002890331],"category_scores_gemma":[0.0003032857,0.0001454979,0.0002478461,0.0004877652,0.0005936566,0.0001794383,0.0002848958,0.001201182,0.001077065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007715841,"about_ca_system_score_gemma":0.0002533486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009109481,"about_ca_topic_score_gemma":0.00001875082,"domain_scores_codex":[0.9959534,0.001948761,0.001110194,0.000166293,0.00009953141,0.0007217673],"domain_scores_gemma":[0.9968806,0.001215672,0.0008401597,0.0008356814,0.0002132718,0.00001463112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001457642,0.00009941916,0.0001416045,0.000004370536,0.0002783526,0.00001117424,0.0008789242,0.00003135961,0.9722575,0.01366545,0.0001274659,0.01104677],"study_design_scores_gemma":[0.002910359,0.0008847936,0.0137804,0.00006397586,0.00008802834,0.00290202,0.00234083,0.000006630332,0.9352297,0.004869551,0.03667882,0.0002448577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7770762,0.2179065,0.00001688738,0.001881802,0.002447461,0.0002478828,0.000003857951,0.00001579875,0.0004036005],"genre_scores_gemma":[0.9886051,0.009526799,0.00002373236,0.0001765296,0.00002601163,0.000006159409,0.000003227074,0.0000312475,0.00160124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2115288,"threshold_uncertainty_score":0.9997007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007514292247473391,"score_gpt":0.2076902180763804,"score_spread":0.200175925828907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}