{"id":"W2941307471","doi":"10.4049/jimmunol.1801632","title":"The Immune Deficiency Pathway Regulates Metabolic Homeostasis in <i>Drosophila</i>","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary; University of Alberta","funders":"University of Alberta; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Technology Futures","keywords":"Biology; Drosophila melanogaster; Immune system; Metabolic pathway; Homeostasis; Immunity; Mutant; Cell biology; Regulator; Signal transduction; Glucose homeostasis; Insulin resistance; Genetics; Insulin; Gene; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005951547,0.0003607153,0.0001301175,0.0003380884,0.0001595032,0.0003048524,0.0001723134,0.0002049404,0.001169801],"category_scores_gemma":[0.00005821033,0.0001315236,0.0001702134,0.00010066,0.0002234475,0.0001531172,0.000244058,0.0004361564,0.0002638077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000492679,"about_ca_system_score_gemma":0.0001484313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001372782,"about_ca_topic_score_gemma":0.002080452,"domain_scores_codex":[0.9999223,0.00001166784,0.000007836148,0.00002263597,0.0000160488,0.00001941346],"domain_scores_gemma":[0.9998937,0.000009693495,0.00004453389,0.000008063888,0.00001160172,0.00003238739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006669719,0.000006742689,0.0005181062,0.00001345197,0.000002869351,0.00003652855,0.000004411513,0.00003816894,0.9987537,0.0000666286,0.00003236206,0.0004604583],"study_design_scores_gemma":[0.00002995617,0.000158142,0.04248755,0.0000207729,0.00002685062,0.0004199759,0.00007733513,0.00240023,0.9514399,0.0001389463,0.002787505,0.00001271242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944453,0.0006637544,0.001997836,0.0001108898,0.00001655792,0.00001540696,0.001077698,0.00008232045,0.001590199],"genre_scores_gemma":[0.9956409,0.0002810518,0.001561924,0.0001040298,0.000003954865,0.00002248941,0.0006360746,0.00003669652,0.001712909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001372782,"threshold_uncertainty_score":0.003913403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007514292247473391,"score_gpt":0.2076902180763804,"score_spread":0.200175925828907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}