{"id":"W2941565779","doi":"10.3390/cells8050395","title":"An Epistatic Interaction between Pnpla2 and Lipe Reveals New Pathways of Adipose Tissue Lipolysis","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Adipose triglyceride lipase; Lipolysis; Lipase; Adipose tissue; Chemistry; Monoacylglycerol lipase; Hormone-sensitive lipase; Catabolism; Internal medicine; Endocrinology; Biochemistry; Enzyme; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002193496,0.0007202979,0.0004083274,0.0005744225,0.0002006635,0.0004332388,0.000224977,0.0004151946,0.002174462],"category_scores_gemma":[0.0002967157,0.0002947918,0.0004754621,0.000346717,0.0002628488,0.0002327896,0.0004995189,0.0005978542,0.0002735127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002653264,"about_ca_system_score_gemma":0.0001853448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003971739,"about_ca_topic_score_gemma":0.0006203555,"domain_scores_codex":[0.9996517,0.00008740828,0.00002569286,0.000108716,0.00008622006,0.00004016406],"domain_scores_gemma":[0.9998043,0.00005539518,0.00006014655,0.00002097201,0.00001551074,0.00004361082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003016602,0.0000193191,0.001934436,0.00002490805,0.00003365977,0.0007438661,0.00001655807,0.0001339419,0.9947416,0.0002843858,0.00004913406,0.00171647],"study_design_scores_gemma":[0.0002979495,0.0008688129,0.3069738,0.00003317443,0.0005872479,0.02304367,0.0003084532,0.02263171,0.6322941,0.002383325,0.01044082,0.0001369446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859461,0.0007869235,0.01091428,0.0001983564,0.00001915223,0.00002659977,0.0007100279,0.0001955717,0.001202945],"genre_scores_gemma":[0.9942531,0.0003217707,0.00369868,0.00009410776,0.0000146293,0.00003139524,0.0005830008,0.0000348631,0.0009685073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002174462,"threshold_uncertainty_score":0.00727433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01032290391113854,"score_gpt":0.2427084337307223,"score_spread":0.2323855298195837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}