{"id":"W2941565779","doi":"10.3390/cells8050395","title":"An Epistatic Interaction between Pnpla2 and Lipe Reveals New Pathways of Adipose Tissue Lipolysis","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Adipose triglyceride lipase; Lipolysis; Lipase; Adipose tissue; Chemistry; Monoacylglycerol lipase; Hormone-sensitive lipase; Catabolism; Internal medicine; Endocrinology; Biochemistry; Enzyme; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001275063,0.0001117781,0.0002052437,0.000040293,0.00002137381,0.00001683779,0.0001177102,0.0001098187,0.00007613748],"category_scores_gemma":[0.00002131289,0.0000991127,0.00004079096,0.00005118231,0.00002733657,0.00000882367,0.00004314668,0.0000444145,0.00004736703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003778383,"about_ca_system_score_gemma":0.00003714157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004121825,"about_ca_topic_score_gemma":0.000006528,"domain_scores_codex":[0.9992799,0.00005613662,0.000201338,0.000251882,0.00007561666,0.0001350921],"domain_scores_gemma":[0.9993892,0.00002638309,0.000109444,0.0003307932,0.00003164709,0.0001125517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002254743,0.00002795349,0.002560694,0.00004849006,0.00003694471,3.158221e-7,0.0001244923,0.000001792664,0.957916,0.00000908428,0.0004895434,0.0387621],"study_design_scores_gemma":[0.0001967445,0.0001813791,0.00461959,0.00001964123,0.00006036755,0.000001367213,0.00006384544,0.000005469806,0.9601634,0.00003808766,0.03452902,0.0001210722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984462,0.0005857409,0.0002400805,0.00002645394,0.0001779627,0.0001291202,0.00003204122,0.000006889747,0.000355547],"genre_scores_gemma":[0.9964462,0.000128891,0.001403188,0.00005600104,0.0003850758,0.000001716096,0.00007521574,0.00001480637,0.001488937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03864102,"threshold_uncertainty_score":0.4041699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01032290391113854,"score_gpt":0.2427084337307223,"score_spread":0.2323855298195837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}