{"id":"W2941757790","doi":"10.1093/neuonc/noz036.059","title":"DIPG-38. DIANHYDROGALACTITOL (VAL-083) WITH AZD1775 INCREASES SURVIVAL IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG), IN VIVO","year":2019,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Delmar (Canada)","funders":"","keywords":"In vivo; Cancer research; Wee1; DNA damage; Cell cycle checkpoint; Cancer; IC50; Cell cycle; Chemistry; Medicine; Pharmacology; In vitro; Internal medicine; Biology; DNA; Cyclin-dependent kinase 1; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009918573,0.0004467672,0.000345803,0.0002830553,0.0001055184,0.0001721451,0.0002293241,0.000203393,0.001041007],"category_scores_gemma":[0.00007075677,0.0001247899,0.0002266255,0.0002389508,0.0002101196,0.0001688806,0.0001458293,0.000665389,0.0002309106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002830412,"about_ca_system_score_gemma":0.0002959506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001512305,"about_ca_topic_score_gemma":0.002571756,"domain_scores_codex":[0.9998772,0.00002108864,0.000009156563,0.00002213488,0.00003684911,0.00003353784],"domain_scores_gemma":[0.9999348,0.000007902302,0.00001654713,0.000005870208,0.000004705487,0.000030185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0010846,0.000355865,0.0003494865,0.00006572581,0.00002365935,0.00009009951,0.00002741801,0.0002218534,0.992737,0.00007616435,0.0001928533,0.004775293],"study_design_scores_gemma":[0.0001253956,0.006789086,0.006967,0.000005603651,0.00004303035,0.0003813156,0.00003334232,0.0009423424,0.9820531,0.00003319463,0.002620403,0.000006142738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966711,0.001266676,0.0004114928,0.0000871874,0.00002650665,0.00002520373,0.0003057784,0.00007820252,0.001127857],"genre_scores_gemma":[0.9966028,0.0007005127,0.0007187212,0.00003405973,0.000008143257,0.00002445183,0.0005011754,0.00001096678,0.001399156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001512305,"threshold_uncertainty_score":0.003482461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01335540551079687,"score_gpt":0.2955085084442396,"score_spread":0.2821531029334428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}