{"id":"W2942554478","doi":"10.1158/1078-0432.ccr-18-2867","title":"Efficacy and Safety Analysis of Nelipepimut-S Vaccine to Prevent Breast Cancer Recurrence: A Randomized, Multicenter, Phase III Clinical Trial","year":2019,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":213,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation","funders":"","keywords":"Medicine; Interim analysis; Placebo; Breast cancer; Internal medicine; Asymptomatic; Adverse effect; Surgery; Erythema; Biopsy; Cancer; Randomized controlled trial; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002860616,0.001007956,0.001360222,0.0002340715,0.0003864438,0.0008106716,0.0006180889,0.001288288,0.003414432],"category_scores_gemma":[0.001403093,0.0003539999,0.001099644,0.0002539621,0.00074282,0.0005946935,0.0002434403,0.0020796,0.0005964763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005484557,"about_ca_system_score_gemma":0.001525718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003271592,"about_ca_topic_score_gemma":0.0005697569,"domain_scores_codex":[0.999272,0.0004553434,0.00004091491,0.00009161565,0.00006185684,0.0000782598],"domain_scores_gemma":[0.9990768,0.000229135,0.0002574752,0.00008994284,0.00008506072,0.0002615484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.926559,0.02613043,0.00180037,0.0005171031,0.0008839343,0.00007632976,0.00009856134,0.0005870123,0.01669892,0.0001790495,0.001307752,0.02516137],"study_design_scores_gemma":[0.7272311,0.2649529,0.00294356,0.00004186887,0.0004282091,0.00007166831,0.00002429777,0.0006689089,0.002308732,0.000140772,0.001175818,0.0000121841],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887771,0.002259068,0.001100882,0.0004623096,0.000186226,0.005116616,0.0006374968,0.00006731044,0.00139298],"genre_scores_gemma":[0.9883389,0.001126966,0.001848321,0.0007102669,0.0002123593,0.005663449,0.0007336082,0.00001874253,0.001347356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003414432,"threshold_uncertainty_score":0.01512861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1100018083514575,"score_gpt":0.5228560650361491,"score_spread":0.4128542566846917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}