{"id":"W2942575504","doi":"10.1016/j.str.2019.03.019","title":"Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor","year":2019,"lang":"en","type":"article","venue":"Structure","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Western Economic Diversification Canada; British Columbia Knowledge Development Fund; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Research Council Canada; Canada Foundation for Innovation; Javna Agencija za Raziskovalno Dejavnost RS; University of Saskatchewan","keywords":"Repressor lexA; Repressor; Bacteriophage; Host (biology); Lysogenic cycle; Biology; Genetics; Chemistry; Cell biology; Gene; Escherichia coli; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007346182,0.0002639019,0.0003609466,0.0001179765,0.0001212135,0.00006561314,0.0002209372,0.0002416573,0.004823531],"category_scores_gemma":[0.00003931364,0.0002031217,0.0000943011,0.0002334444,0.0001290747,0.000517452,0.0001113765,0.0002253016,0.00008926175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000528204,"about_ca_system_score_gemma":0.0000459629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001072031,"about_ca_topic_score_gemma":0.00009262567,"domain_scores_codex":[0.9983523,0.00008069757,0.0003992915,0.0005162981,0.0003734279,0.0002779752],"domain_scores_gemma":[0.9988548,0.00003423211,0.0002783298,0.0006071953,0.0001421814,0.00008322113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009347626,0.000003477624,0.001258766,0.0001093884,0.000009984957,0.000004522839,0.00109817,0.00006177922,0.9949921,0.001691819,0.0002252195,0.0004512775],"study_design_scores_gemma":[0.0006074573,0.0001432778,0.0561733,0.00004723307,0.000021967,0.00002161375,0.0001329044,0.00004779661,0.9340208,0.00707458,0.001453385,0.0002556703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952005,0.0002142144,0.00003729378,0.00004733569,0.002255044,0.0003063757,0.00006526028,0.00008953521,0.00178442],"genre_scores_gemma":[0.9979632,0.000005824824,0.001071423,0.0001386091,0.0003514059,0.000003766023,0.00008856666,0.000027848,0.0003492957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0609713,"threshold_uncertainty_score":0.9960862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005066335167501742,"score_gpt":0.2108877786913073,"score_spread":0.2058214435238056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}