{"id":"W2942682252","doi":"10.1182/bloodadvances.2018030171","title":"GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia","year":2019,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia; Ottawa Hospital","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Pharmacyclics; Kite Pharma; Health Resources and Services Administration; National Institutes of Health; Swedish Orphan Biovitrum; Janssen Scientific Affairs; Mundipharma EDO; Astellas Pharma; Adaptive Biotechnologies; bluebird bio; Chimerix; Medical College of Wisconsin; Takeda Oncology; University of Minnesota; Karyopharm Therapeutics; U.S. Navy; Celgene; U.S. Department of Defense; Sanofi; U.S. Department of Health and Human Services; Astellas Pharma US; National Center for Advancing Translational Sciences; HistoGenetics; Sanofi Genzyme; Patient-Centered Outcomes Research Institute; Bristol-Myers Squibb; Medac; Jazz Pharmaceuticals; Be The Match Foundation; Spectrum Pharmaceuticals; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Incyte; Pfizer; Amgen; Atara Biotherapeutics; National Cancer Institute; Gilead Sciences","keywords":"Medicine; Hazard ratio; Internal medicine; Gastroenterology; Total body irradiation; Busulfan; Proportional hazards model; Umbilical cord; Confidence interval; Univariate analysis; Transplantation; Methotrexate; Hematopoietic stem cell transplantation; Cyclophosphamide; Multivariate analysis; Immunology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007516917,0.0001737035,0.0002943448,0.000137613,0.00003001044,0.00001324749,0.00005422499,0.00005904331,0.00001799687],"category_scores_gemma":[0.000005090838,0.000138289,0.00003415701,0.0001587338,0.00002559003,0.0002407493,0.00000433945,0.00009192844,0.00001228793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003215104,"about_ca_system_score_gemma":0.00006938677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001103678,"about_ca_topic_score_gemma":0.00002017743,"domain_scores_codex":[0.998927,0.00001979005,0.0002657472,0.0003346216,0.0002291697,0.0002236979],"domain_scores_gemma":[0.9994408,0.0001726187,0.0001136439,0.0001226879,0.00007283059,0.00007734097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009343253,0.0002336037,0.9922088,0.002936295,0.00004777995,0.00004583836,0.001855184,0.00008470922,0.0009958544,0.0001145772,0.000004245544,0.0005387953],"study_design_scores_gemma":[0.04337262,0.002709663,0.8819093,0.0007489236,0.001968971,0.0001468932,0.0005046569,0.0002280793,0.0669148,0.0005965395,0.0002239069,0.0006757042],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958133,0.0004828824,0.001191334,0.00003577864,0.0001018393,0.001454525,0.00006367707,0.00002882265,0.0008278893],"genre_scores_gemma":[0.9933779,0.001043451,0.005025031,0.00006555043,0.00004844075,0.00009978209,0.0001344639,0.00002768228,0.0001777255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1102995,"threshold_uncertainty_score":0.5639263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004829612228905772,"score_gpt":0.2307096164372983,"score_spread":0.2258800042083926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}