{"id":"W2942682252","doi":"10.1182/bloodadvances.2018030171","title":"GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia","year":2019,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia; Ottawa Hospital","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Pharmacyclics; Kite Pharma; Health Resources and Services Administration; National Institutes of Health; Swedish Orphan Biovitrum; Janssen Scientific Affairs; Mundipharma EDO; Astellas Pharma; Adaptive Biotechnologies; bluebird bio; Chimerix; Medical College of Wisconsin; Takeda Oncology; University of Minnesota; Karyopharm Therapeutics; U.S. Navy; Celgene; U.S. Department of Defense; Sanofi; U.S. Department of Health and Human Services; Astellas Pharma US; National Center for Advancing Translational Sciences; HistoGenetics; Sanofi Genzyme; Patient-Centered Outcomes Research Institute; Bristol-Myers Squibb; Medac; Jazz Pharmaceuticals; Be The Match Foundation; Spectrum Pharmaceuticals; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Incyte; Pfizer; Amgen; Atara Biotherapeutics; National Cancer Institute; Gilead Sciences","keywords":"Medicine; Hazard ratio; Internal medicine; Gastroenterology; Total body irradiation; Busulfan; Proportional hazards model; Umbilical cord; Confidence interval; Univariate analysis; Transplantation; Methotrexate; Hematopoietic stem cell transplantation; Cyclophosphamide; Multivariate analysis; Immunology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001556854,0.0002086313,0.0002964344,0.0005496012,0.0001940403,0.0004063201,0.0002181478,0.0002181597,0.00100912],"category_scores_gemma":[0.003554108,0.0001116953,0.000456794,0.000703632,0.0003027395,0.0004501491,0.0005205589,0.0005904931,0.0001140733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000316214,"about_ca_system_score_gemma":0.0003454084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001005742,"about_ca_topic_score_gemma":0.001160197,"domain_scores_codex":[0.9992328,0.0003093257,0.00006991351,0.0001192201,0.0001563692,0.0001123161],"domain_scores_gemma":[0.9965827,0.001162352,0.00168178,0.0001468907,0.0001503089,0.0002760981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000308422,0.00001228896,0.9944659,0.0000122107,0.00006024576,0.00009883183,0.00002812533,0.0002804269,0.00008087778,0.00003552931,0.0001186836,0.00449856],"study_design_scores_gemma":[0.00002983563,0.0003494218,0.9953838,0.00001941264,0.0000971056,0.001491148,0.0001312956,0.001524638,0.0002128568,0.0001179463,0.0006348563,0.000007719178],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985067,0.0007708262,0.0002176835,0.00004406926,0.000006071008,0.000002903289,0.0002594049,0.000004689759,0.000187645],"genre_scores_gemma":[0.9994285,0.0001526754,0.00008662786,0.000009213712,0.0000115239,0.000003359965,0.0002781657,0.000001456623,0.000028518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001556854,"threshold_uncertainty_score":0.008233547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004829612228905772,"score_gpt":0.2307096164372983,"score_spread":0.2258800042083926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}