{"id":"W2942841445","doi":"10.1016/j.molimm.2019.04.022","title":"Modulation of cathelicidins, IFNβ and TNFα by bovine alpha-herpesviruses is dependent on the stage of the infectious cycle","year":2019,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Innate immune system; Biology; Immunology; Tumor necrosis factor alpha; Immune system; Cathelicidin; Downregulation and upregulation; Interferon; Viral replication; Microbiology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001901307,0.000160829,0.0002260916,0.000146832,0.0001257274,0.0005801431,0.0001012198,0.0002310676,0.0008702663],"category_scores_gemma":[0.000299959,0.0001175798,0.0001798585,0.0001160806,0.0002048945,0.0002780577,0.0001498225,0.0004680444,0.0001716036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000315176,"about_ca_system_score_gemma":0.0002016395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003375264,"about_ca_topic_score_gemma":0.0004847682,"domain_scores_codex":[0.9997813,0.00005482174,0.00001649385,0.00002480624,0.00003331754,0.00008923891],"domain_scores_gemma":[0.9997649,0.00005590624,0.00006621282,0.00002261032,0.00003853069,0.0000518239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001354827,0.00002938423,0.0009231325,0.00003429172,0.00000418357,0.00003931156,0.0000344453,0.00001986748,0.9955881,0.00009579919,0.0000211132,0.001855686],"study_design_scores_gemma":[0.0000630976,0.001469802,0.06052712,0.00004497833,0.00002731547,0.0002922196,0.0002303904,0.0007410226,0.9342858,0.0002249809,0.002082244,0.00001108858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994235,0.004051274,0.0005030156,0.00004126917,0.00003563707,0.00001150907,0.00009727235,0.000009758208,0.001015204],"genre_scores_gemma":[0.9978747,0.0009940809,0.0002963869,0.00001991794,0.00001085303,0.000008312414,0.00008021313,0.000003978151,0.0007116504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008702663,"threshold_uncertainty_score":0.002911329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006223197258235456,"score_gpt":0.2366958121183494,"score_spread":0.230472614860114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}