{"id":"W2942933849","doi":"10.1371/journal.pone.0216370","title":"Differential actinodin1 regulation in embryonic development and adult fin regeneration in Danio rerio","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Enhancer; Biology; Zebrafish; Ectoderm; Cell biology; Blastema; Mesenchyme; Regulation of gene expression; Fish fin; Genetics; Regeneration (biology); Gene expression; Embryonic stem cell; Gene; Mesenchymal stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008534913,0.00009689388,0.0001170951,0.00006625796,0.00002903088,0.00001057421,0.00004609706,0.0001580911,0.00003060699],"category_scores_gemma":[0.00002213608,0.0001005117,0.00001123898,0.00006685515,0.00001711573,0.000007597081,0.0000514334,0.00006242647,0.00001680134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000384435,"about_ca_system_score_gemma":0.00005022264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006887237,"about_ca_topic_score_gemma":0.0005478536,"domain_scores_codex":[0.9992766,0.00004620338,0.0001827012,0.0002727173,0.00008508191,0.0001366864],"domain_scores_gemma":[0.999772,0.000004940833,0.00005404407,0.0001171032,0.00002841398,0.00002348744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001134103,0.0001399928,0.1299734,0.00002546853,0.00002116831,3.604227e-7,0.0001180108,0.00001417056,0.8668468,0.0000554953,0.00001451621,0.002677236],"study_design_scores_gemma":[0.0005022331,0.00005146889,0.3770281,0.00003819724,0.000003142193,9.617012e-7,0.00001754708,0.0002090519,0.621904,0.0000275504,0.0001199294,0.00009782484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991691,0.00009548987,0.00005059446,0.0001520448,0.00003874289,0.0002443166,0.000001204556,0.000005750246,0.0002427515],"genre_scores_gemma":[0.9961331,0.00007646241,0.001574027,0.00004782986,0.0000410814,0.00002497088,0.0004784485,0.000008206198,0.001615812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2470547,"threshold_uncertainty_score":0.4098749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01258735175330488,"score_gpt":0.2007490157489363,"score_spread":0.1881616639956314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}