{"id":"W2943118971","doi":"10.1667/rr15323.1","title":"Characterization of Radioprotective, Radiomitigative and Bystander Signaling Modulating Effects of Endogenous Metabolites – Phenylacetate, Ursodeoxycholate and Tauroursodeoxycholate – on HCT116 Human Colon Carcinoma Cell Line","year":2019,"lang":"en","type":"article","venue":"Radiation Research","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National CFIDS Foundation","keywords":"Bystander effect; Phenylacetate; Clonogenic assay; Cancer research; Endogeny; Stem cell; Pharmacology; Cell culture; Carcinogen; Ionizing radiation; Chemistry; Medicine; Cell; Biology; Immunology; Irradiation; Internal medicine; Cell biology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001623499,0.0002493401,0.0006852677,0.0007917476,0.0001895163,0.00004478908,0.0001000772,0.0002008269,0.00002605438],"category_scores_gemma":[0.0006004286,0.0002393759,0.00007999588,0.0006443071,0.0001958509,0.0003069183,0.00004793748,0.0005652562,0.000004849955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001420218,"about_ca_system_score_gemma":0.0001045617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000853344,"about_ca_topic_score_gemma":0.000001017268,"domain_scores_codex":[0.9970104,0.0007301063,0.0005362452,0.0005340272,0.0007903514,0.0003988494],"domain_scores_gemma":[0.9972732,0.0011478,0.0004380811,0.000359945,0.0005774106,0.000203558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004178666,0.000167128,0.03601182,0.001417137,0.0001079806,0.00001095226,0.002762657,0.0002091027,0.9555565,0.0002689326,0.000002782701,0.003067133],"study_design_scores_gemma":[0.004624117,0.002107962,0.2250566,0.0002252317,0.00006979189,0.00001385097,0.0001084456,0.006509397,0.7609929,0.000118069,0.00001889487,0.000154625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949934,0.001083028,0.000164577,0.0001454011,0.00007538547,0.002964617,0.00003638549,0.00003390178,0.0005033318],"genre_scores_gemma":[0.9988742,0.000175144,0.0003922202,0.00004196456,0.00008640651,0.00006878212,0.00007532528,0.00005800867,0.0002279887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1945635,"threshold_uncertainty_score":0.9761465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02612936907402627,"score_gpt":0.3080124884562232,"score_spread":0.281883119382197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}