{"id":"W2943118971","doi":"10.1667/rr15323.1","title":"Characterization of Radioprotective, Radiomitigative and Bystander Signaling Modulating Effects of Endogenous Metabolites – Phenylacetate, Ursodeoxycholate and Tauroursodeoxycholate – on HCT116 Human Colon Carcinoma Cell Line","year":2019,"lang":"en","type":"article","venue":"Radiation Research","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National CFIDS Foundation","keywords":"Bystander effect; Phenylacetate; Clonogenic assay; Cancer research; Endogeny; Stem cell; Pharmacology; Cell culture; Carcinogen; Ionizing radiation; Chemistry; Medicine; Cell; Biology; Immunology; Irradiation; Internal medicine; Cell biology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008888932,0.0002620256,0.0002120721,0.0002166252,0.0000942402,0.0001177539,0.00008500431,0.0001590136,0.0008580495],"category_scores_gemma":[0.00008831842,0.0000582156,0.0001851887,0.0002024819,0.00009656521,0.0001088737,0.00007186973,0.0002528679,0.0001339225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008729863,"about_ca_system_score_gemma":0.0001276702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004993018,"about_ca_topic_score_gemma":0.0008977362,"domain_scores_codex":[0.9999409,0.00001107946,0.000007074467,0.00001152901,0.00001751332,0.00001190881],"domain_scores_gemma":[0.9999226,0.00001614173,0.00002093007,0.00001103491,0.00001911154,0.00001019072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008638798,0.00002110598,0.0001847802,0.0000406797,0.000003810112,0.00002085724,0.00001061582,0.00004179789,0.9985628,0.0000139408,0.00001166854,0.001001641],"study_design_scores_gemma":[0.00000614098,0.0006920799,0.006956712,0.000005635646,0.00001909975,0.00007346956,0.00002030341,0.0001433535,0.9912384,0.000008205659,0.000834487,0.000001992122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952649,0.002235843,0.0009734856,0.00004107585,0.00001252534,0.00002945731,0.0004715539,0.0000250832,0.0009460016],"genre_scores_gemma":[0.9937404,0.001999648,0.001304253,0.0000321215,0.000008765659,0.00003819937,0.0009750886,0.000009681348,0.001891845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008580495,"threshold_uncertainty_score":0.00287044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02612936907402627,"score_gpt":0.3080124884562232,"score_spread":0.281883119382197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}