{"id":"W2943164804","doi":"10.3899/jrheum.190008","title":"Placebo Response in Rheumatoid Arthritis Clinical Trials","year":2019,"lang":"en","type":"review","venue":"The Journal of Rheumatology","topic":"Pain Management and Placebo Effect","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council","keywords":"Medicine; Placebo; Rheumatoid arthritis; Internal medicine; Abatacept; Tocilizumab; Rheumatology; Randomized controlled trial; Clinical trial; Rituximab; Erythrocyte sedimentation rate; Tofacitinib; Pathology; Lymphoma; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","insufficient_payload"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.1826571,0.0004810825,0.006669833,0.0008183055,0.0000889486,0.00005846284,0.001727568,0.000572641,0.0002055377],"category_scores_gemma":[0.1122676,0.000275236,0.001425072,0.0005469203,0.0003109508,0.0001515465,0.0002435282,0.002158295,0.00084742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008465501,"about_ca_system_score_gemma":0.0006883432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001263342,"about_ca_topic_score_gemma":0.00001288586,"domain_scores_codex":[0.8170056,0.1756991,0.005795025,0.0004016592,0.0005163152,0.0005822494],"domain_scores_gemma":[0.803113,0.1914132,0.004729332,0.0006002046,0.00003726407,0.0001070075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005996996,0.0001079945,0.0003674428,0.002181938,0.0001765841,0.0001832023,0.0001079195,0.00001227603,0.000004587571,0.0004401788,0.01136975,0.9790511],"study_design_scores_gemma":[0.002217551,0.0003964896,0.000009032286,0.01614321,0.0002055971,0.007969537,0.00002413613,0.00006073985,0.000002142513,0.0001960155,0.9724955,0.0002800298],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002871251,0.9917836,0.0002625666,0.000320806,0.003010629,0.001422121,0.00001232932,0.00001977347,0.0002969357],"genre_scores_gemma":[0.001169852,0.9983436,0.00002546319,0.0001246245,0.00002919032,0.00001545366,0.000001368284,0.00005127307,0.0002392014],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9787711,"threshold_uncertainty_score":0.99997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2243223573220652,"score_gpt":0.4491619380111492,"score_spread":0.2248395806890841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}