{"id":"W2943226571","doi":"10.1111/hae.13762","title":"The changing face of immune tolerance induction in haemophilia A with the advent of emicizumab","year":2019,"lang":"en","type":"article","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Clinical Evaluative Sciences; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Grifols","keywords":"Haemophilia; Medicine; Haemophilia A; Concomitant; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004391897,0.0001607989,0.0004655118,0.0003924,0.0003447506,0.001593851,0.0003577825,0.001216616,0.002352201],"category_scores_gemma":[0.007266285,0.00009687289,0.0003658653,0.0004325603,0.001047524,0.001604619,0.0005033514,0.0028292,0.000317955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00108599,"about_ca_system_score_gemma":0.001094752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006415442,"about_ca_topic_score_gemma":0.001028629,"domain_scores_codex":[0.9982596,0.001030114,0.0001577662,0.0001419698,0.0002914837,0.0001191085],"domain_scores_gemma":[0.9947449,0.002955853,0.001044835,0.000158909,0.0007116229,0.0003838846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001458984,0.0002403769,0.01932207,0.002980144,0.0002063848,0.002763622,0.0006284032,0.0008424537,0.004095319,0.03363005,0.04922427,0.884608],"study_design_scores_gemma":[0.0003372492,0.002331057,0.06202916,0.007337793,0.0005131611,0.02476336,0.001836715,0.002028368,0.004585051,0.05834674,0.8357629,0.0001285125],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07316904,0.6500703,0.0064611,0.2394713,0.004429159,0.00006487621,0.0002063276,0.00008721893,0.02604072],"genre_scores_gemma":[0.5405684,0.3705284,0.01078604,0.0595079,0.01306977,0.0001195026,0.0002841246,0.00004896083,0.005087112],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004391897,"threshold_uncertainty_score":0.02322686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01529455889633354,"score_gpt":0.2728471354671899,"score_spread":0.2575525765708563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}