{"id":"W2943313378","doi":"10.1093/intimm/dxz016","title":"Natural killer cells kill<i>Burkholderia cepacia</i>complex via a contact-dependent and cytolytic mechanism","year":2019,"lang":"en","type":"article","venue":"International Immunology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Cystic Fibrosis Canada; Health Research Board","keywords":"Burkholderia cepacia complex; Perforin; Microbiology; Cytolysis; Biology; Burkholderia; Innate immune system; Burkholderia cenocepacia; Effector; Immunology; Immune system; Bacteria; Cytotoxicity; CD8","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001407434,0.0002812599,0.0002001098,0.00009426169,0.00009028694,0.0001932397,0.0001544816,0.0002583798,0.001653648],"category_scores_gemma":[0.000187284,0.00005633761,0.0001977467,0.00004183723,0.0002460728,0.0002616542,0.000302372,0.0003063704,0.000372912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001139842,"about_ca_system_score_gemma":0.0001205666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001212305,"about_ca_topic_score_gemma":0.0002254022,"domain_scores_codex":[0.99985,0.00003373008,0.00001400301,0.00002495987,0.00003124138,0.00004603932],"domain_scores_gemma":[0.9999268,0.00001723044,0.00001972551,0.00001062305,0.00001249902,0.00001311811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000196119,0.00007060134,0.001059945,0.0001285487,0.000007564409,0.0002367386,0.00004396997,0.00006359016,0.9874036,0.0002766525,0.0001118981,0.01040076],"study_design_scores_gemma":[0.0001641702,0.002774565,0.01211247,0.00003977735,0.00004036755,0.002566569,0.0001499479,0.001235296,0.9729049,0.0004933986,0.007509592,0.000008883215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855673,0.005046219,0.004368076,0.0002918235,0.0001020355,0.00009768767,0.00007781399,0.00008259606,0.004366526],"genre_scores_gemma":[0.9955011,0.001041115,0.001430814,0.000106754,0.00003464727,0.00003479412,0.00006044218,0.000003336487,0.001787031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001653648,"threshold_uncertainty_score":0.005531967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01059063997712866,"score_gpt":0.2828290836093722,"score_spread":0.2722384436322435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}