{"id":"W2943379297","doi":"10.1016/j.molmed.2019.03.006","title":"Vascular Regenerative Cell Exhaustion in Diabetes: Translational Opportunities to Mitigate Cardiometabolic Risk","year":2019,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Cardiac and Coronary Surgery Techniques","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hamilton Health Sciences; Western University; St. Michael's Hospital; Population Health Research Institute; McMaster University","funders":"Canadian Institutes of Health Research; Boehringer Ingelheim; Heart and Stroke Foundation of Canada; Canada Research Chairs; AstraZeneca; Eli Lilly and Company; Sanofi; Abbott Laboratories; Merck; Amgen","keywords":"Progenitor cell; Medicine; Bone marrow; Stem cell; Population; Type 2 diabetes; Inflammation; Endothelial progenitor cell; Internal medicine; Diabetes mellitus; Endocrinology; Immunology; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007617689,0.000720655,0.001437175,0.00135193,0.0002183559,0.001344599,0.0007486235,0.00108308,0.004645579],"category_scores_gemma":[0.001035059,0.0001965577,0.0005009513,0.001129753,0.000471372,0.001164934,0.0008027515,0.00247726,0.001722955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000431024,"about_ca_system_score_gemma":0.001114243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006566406,"about_ca_topic_score_gemma":0.00165864,"domain_scores_codex":[0.9998171,0.0000309538,0.00002564013,0.00003493498,0.00006682255,0.00002457638],"domain_scores_gemma":[0.9994218,0.00032788,0.00006645176,0.00001299526,0.0001264379,0.00004448267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001393292,0.0000920625,0.0001981098,0.01452481,0.0001137657,0.0000990984,0.00003183392,0.0002986052,0.00148981,0.004521046,0.02628258,0.9522089],"study_design_scores_gemma":[0.00005484468,0.000200972,0.0009442613,0.007234964,0.0002540444,0.0006133451,0.00008924698,0.0001814647,0.0005695743,0.004935666,0.9848903,0.00003134489],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008154377,0.9985791,0.000129941,0.000429353,0.000255584,0.00000259447,0.00001857295,0.000006389329,0.0004968854],"genre_scores_gemma":[0.0005568391,0.9983177,0.0001667421,0.0003288577,0.000305378,0.000004332992,0.00002552814,0.000001103239,0.0002934935],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004645579,"threshold_uncertainty_score":0.01554102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06764495990853674,"score_gpt":0.3434560756513881,"score_spread":0.2758111157428513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}