{"id":"W2943387000","doi":"10.1101/625285","title":"Efficient and robust NK-Cell transduction with Baboon Envelope pseudotyped lentivector: a major tool for immunotherapy","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Cancer Institute; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fondation ARC pour la Recherche sur le Cancer; Institut National de la Santé et de la Recherche Médicale","keywords":"Biology; Vesicular stomatitis virus; Transduction (biophysics); Baboon; CD19; Virology; Measles virus; Cell culture; Molecular biology; Antigen; Immunology; Virus; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004665527,0.0004721059,0.0004795228,0.0002364528,0.0001399583,0.0006211826,0.0002923378,0.000319854,0.001186804],"category_scores_gemma":[0.0001886646,0.0001714111,0.0002099716,0.0001813337,0.0002919042,0.0003141323,0.0004230659,0.001236517,0.0008498354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002052942,"about_ca_system_score_gemma":0.0001755709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002615349,"about_ca_topic_score_gemma":0.0002544527,"domain_scores_codex":[0.9996002,0.00008533382,0.00005095738,0.00007296205,0.0001212177,0.00006931771],"domain_scores_gemma":[0.9998796,0.00002215711,0.00002478503,0.00002732491,0.00001905888,0.00002701254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002680361,0.00002066842,0.0000681767,0.0000282181,0.000003760996,0.0000180527,0.000008669314,0.00006139804,0.9978727,0.0001077294,0.00005582779,0.00172806],"study_design_scores_gemma":[0.00002016439,0.0002450073,0.001249097,0.00000983835,0.0000188034,0.0003427813,0.00001302425,0.001584569,0.9910453,0.00007213438,0.005393527,0.000005737017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.875273,0.004958182,0.1123601,0.0004058046,0.0001911524,0.0004612762,0.001123226,0.001266149,0.003961136],"genre_scores_gemma":[0.9648101,0.001787988,0.02660174,0.000102274,0.00003436241,0.0002233727,0.001170618,0.0001612984,0.005108081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001186804,"threshold_uncertainty_score":0.003970325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01708927747776947,"score_gpt":0.2381834091941415,"score_spread":0.221094131716372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}