{"id":"W2943549050","doi":"10.1093/pm/pnz067","title":"The Impact of Surgical Amputation and Valproic Acid on Pain and Functional Trajectory: Results from the Veterans Integrated Pain Evaluation Research (VIPER) Randomized, Double-Blinded Placebo-Controlled Trial","year":2019,"lang":"en","type":"article","venue":"Pain Medicine","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Perioperative; Anesthesia; Placebo; Randomized controlled trial; Amputation; Brief Pain Inventory; Visual analogue scale; Pain medicine; Chronic pain; Surgery; Physical therapy; Anesthesiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.1028689,0.000203276,0.0005100446,0.0001216745,0.0002376414,0.00003854484,0.0001476993,0.000195414,0.00005964008],"category_scores_gemma":[0.01868509,0.00009625324,0.0001560683,0.0002334692,0.0006777005,0.000006171924,0.00003401296,0.0004478752,0.000003360918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008940213,"about_ca_system_score_gemma":0.0003596465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000906776,"about_ca_topic_score_gemma":0.0001252312,"domain_scores_codex":[0.9776462,0.01978079,0.0006438001,0.0004900174,0.001120765,0.000318408],"domain_scores_gemma":[0.9839387,0.01485177,0.000183216,0.0003901871,0.0005284913,0.0001076731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9358149,0.00005989744,0.0000487396,0.000009161425,0.0002343659,0.000001558924,0.0005776694,0.0002696661,0.04515819,0.000009666982,0.005802245,0.01201393],"study_design_scores_gemma":[0.9423497,0.004764958,0.000138351,0.0001278187,0.00005184909,0.000002726986,0.00070774,0.04901651,0.001890932,0.0001323013,0.0007043935,0.000112663],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890488,0.002194208,0.0006575242,0.002496571,0.0001358414,0.005176813,0.00002035388,0.000007985911,0.0002619337],"genre_scores_gemma":[0.9977086,0.0003128285,0.00001563422,0.00007018095,0.0006492421,0.000427752,0.000588097,0.00001954663,0.0002081401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0841838,"threshold_uncertainty_score":0.9895809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05255686669686859,"score_gpt":0.3732484741260391,"score_spread":0.3206916074291705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}