{"id":"W2943556757","doi":"10.1111/bpa.12732","title":"cIMPACT‐NOW: a practical summary of diagnostic points from Round 1 updates","year":2019,"lang":"en","type":"article","venue":"Brain Pathology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Anaplastic astrocytoma; Glioma; Glioblastoma; IDH1; Astrocytoma; Medicine; Cancer research; Mutant; Oncology; Pathology; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02346825,0.001586723,0.001489329,0.006302062,0.001682181,0.007307505,0.003485229,0.00611264,0.03434087],"category_scores_gemma":[0.07738626,0.00105964,0.001929903,0.00312406,0.0009188504,0.005340314,0.005030239,0.008851186,0.02837889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003713581,"about_ca_system_score_gemma":0.009672769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005102221,"about_ca_topic_score_gemma":0.006449682,"domain_scores_codex":[0.9880294,0.003467429,0.002378376,0.0006918912,0.004385583,0.001047227],"domain_scores_gemma":[0.9305218,0.01031839,0.005710619,0.003369278,0.04247707,0.007602711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009003792,0.00002549214,0.0005548319,0.0002606554,0.0000117017,0.0002092239,0.00005831798,0.0002704454,0.000184205,0.001409944,0.9086812,0.08824395],"study_design_scores_gemma":[0.00006253969,0.00008780729,0.00169773,0.001419807,0.00002977997,0.0006111089,0.0001186656,0.0002697787,0.0003473882,0.002162873,0.9931385,0.00005406158],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.005224117,0.03920458,0.04007422,0.6006188,0.1087185,0.004491563,0.01819157,0.008353259,0.1751233],"genre_scores_gemma":[0.04821154,0.09174685,0.1800715,0.2882253,0.1513481,0.008837269,0.08176817,0.005077132,0.1447142],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.03434087,"threshold_uncertainty_score":0.1241135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01690641062192487,"score_gpt":0.3033653527626561,"score_spread":0.2864589421407313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}