{"id":"W2943733498","doi":"10.1136/gutjnl-2018-317855","title":"Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice","year":2019,"lang":"en","type":"article","venue":"Gut","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":216,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institutes of Health; Crohn's and Colitis Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; Kenneth Rainin Foundation; Crohn's and Colitis Foundation of America","keywords":"Microbiome; Offspring; Pregnancy; Immune system; Immunology; Biology; Gut flora; Acquired immune system; Immunity; Physiology; Bioinformatics; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002097877,0.0003075401,0.0003238651,0.0003511713,0.0002149554,0.0003459209,0.0001882689,0.0003732533,0.001719126],"category_scores_gemma":[0.0003708022,0.0001769838,0.0002655749,0.0001708397,0.0003206215,0.0002189649,0.0003981347,0.0007701595,0.0002250395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001557348,"about_ca_system_score_gemma":0.0001683175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003308699,"about_ca_topic_score_gemma":0.0003308762,"domain_scores_codex":[0.9997498,0.00004349626,0.00002950546,0.00007060355,0.00005390252,0.00005266783],"domain_scores_gemma":[0.9996173,0.00005327052,0.0001930948,0.00004873966,0.00001865846,0.00006885597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002057915,0.000254231,0.03147799,0.000161822,0.00005308615,0.001579322,0.0003111234,0.00009104156,0.9536419,0.0002219983,0.000201822,0.009947752],"study_design_scores_gemma":[0.0001125094,0.006669595,0.4918161,0.0002058127,0.0002892309,0.02013997,0.001490755,0.001227793,0.4668369,0.0006144454,0.01054531,0.0000515552],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971218,0.000775882,0.001140681,0.00009299514,0.00002595854,0.00001375787,0.0003399579,0.00004737797,0.0004417505],"genre_scores_gemma":[0.9951255,0.0009161227,0.002046889,0.0001413552,0.0000185292,0.00007191384,0.0005293207,0.00002518654,0.00112515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001719126,"threshold_uncertainty_score":0.005751014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006976725951263357,"score_gpt":0.2079798004921854,"score_spread":0.201003074540922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}