{"id":"W2943847800","doi":"10.1210/js.2019-sat-546","title":"SAT-546 Discovering the Function of IGSF1 and Its Role in the Hypothalamic-Pituitary-Thyroid Axis","year":2019,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cell biology; Intracellular; Biology; Transmembrane protein; Extracellular; Pituitary gland; Hormone; Receptor; Internal medicine; Endocrinology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001586264,0.000232511,0.000162596,0.0002394253,0.0002094437,0.0003504979,0.0002362387,0.0004175078,0.003334548],"category_scores_gemma":[0.00008892807,0.0001627363,0.0003567794,0.000236423,0.0001780781,0.0002242914,0.000252488,0.0007659752,0.000927715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004142269,"about_ca_system_score_gemma":0.0002297694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001005703,"about_ca_topic_score_gemma":0.001667458,"domain_scores_codex":[0.9999077,0.00001068652,0.000007881106,0.00002359474,0.00002719372,0.00002296633],"domain_scores_gemma":[0.9999396,0.00001190935,0.00001062581,0.000007157542,0.00001198126,0.00001874385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005525057,0.000009779482,0.0004910523,0.00001941015,0.000002607358,0.00003026708,0.00001210315,0.00005425214,0.9969234,0.0002324734,0.00005859201,0.002110787],"study_design_scores_gemma":[0.00004211405,0.0003684111,0.01418628,0.00002226398,0.0000347641,0.0004704051,0.0001080954,0.005790735,0.9599913,0.0002690018,0.01870548,0.00001112785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9751738,0.003161765,0.01318614,0.000670737,0.0001332209,0.00003206704,0.001232544,0.0001585664,0.006251095],"genre_scores_gemma":[0.9674723,0.00174014,0.01526837,0.0002273782,0.000032239,0.0000355327,0.00332854,0.00004547815,0.01184998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003334548,"threshold_uncertainty_score":0.01115519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006544910268204649,"score_gpt":0.227320419321023,"score_spread":0.2207755090528183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}