{"id":"W2943888979","doi":"10.1161/jaha.118.011630","title":"Arterial Stiffness Due to Carotid Calcification Disrupts Cerebral Blood Flow Regulation and Leads to Cognitive Deficits","year":2019,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Neurological Disease Mechanisms and Treatments","field":"Neuroscience","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut Universitaire de Gériatrie de Montréal; Montreal Heart Institute; Université Laval; Centre hospitalier universitaire de Québec; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Cerebral blood flow; Medicine; Internal medicine; Arterial stiffness; Cognitive decline; Hippocampus; Cardiology; Endocrinology; Neuroscience; Blood pressure; Dementia; Psychology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000217894,0.0001084008,0.0002925989,0.00007647642,0.0001215558,0.00007291159,0.0001025017,0.00003028894,0.00001572494],"category_scores_gemma":[0.0009980397,0.00007677686,0.00009968304,0.0003440755,0.00001980488,0.0001535373,0.00005131358,0.000109725,0.00005091122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001126931,"about_ca_system_score_gemma":0.00003432106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001217257,"about_ca_topic_score_gemma":0.000005477241,"domain_scores_codex":[0.9985338,0.0003557687,0.0002623695,0.0002124484,0.0004471423,0.0001884961],"domain_scores_gemma":[0.9989229,0.0003062344,0.0003863484,0.0001111001,0.0001352731,0.0001381854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004630644,0.0002084968,0.1813624,0.000004626232,0.00002342309,0.000004402073,0.0003036918,0.0002782,0.8154763,0.00008876505,0.0001351645,0.001651437],"study_design_scores_gemma":[0.0006628711,0.0005173543,0.9405123,0.00002564097,0.00007729199,0.00003000703,0.00003872123,0.0001275753,0.05764588,0.0002483179,0.00002722382,0.00008684544],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969028,0.000001785089,0.000162357,0.001973313,0.000443499,0.0004307334,0.00003930447,0.00001123192,0.0000350332],"genre_scores_gemma":[0.9979153,0.000001510856,0.000189053,0.001634879,0.000126311,0.000008785015,0.000001077583,0.00001118251,0.0001118654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7591498,"threshold_uncertainty_score":0.3130869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01682963552572272,"score_gpt":0.2683479762497684,"score_spread":0.2515183407240457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}