{"id":"W2943896988","doi":"10.1158/1538-7445.sabcs18-p6-13-04","title":"Abstract P6-13-04: Estrogen-alone based hormone replacement therapy (HRT) reduces breast cancer (BrCa) incidence and mortality whereas estrogen plus progestin Provera based HRT increases both BrCa incidence and BrCa mortality: A comparative analysis of Women's Health Initiative trials","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Risks and Factors","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; Centre for Advancing Health Outcomes; University of Victoria; University of British Columbia; Providence Health Care; BC Cancer Agency","funders":"","keywords":"Medicine; Hazard ratio; Hormone replacement therapy (female-to-male); Breast cancer; Gynecology; Estrogen; Internal medicine; Incidence (geometry); Progestin; Cancer; Confidence interval; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00926722,0.001120935,0.00246517,0.001075201,0.0002288677,0.001697254,0.0007125186,0.00154118,0.01874354],"category_scores_gemma":[0.01912964,0.0002895399,0.004182647,0.00155105,0.0006022959,0.0008858673,0.0005384273,0.001692448,0.0008651357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007179863,"about_ca_system_score_gemma":0.001112778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008968988,"about_ca_topic_score_gemma":0.001494341,"domain_scores_codex":[0.9935274,0.00498912,0.0005954904,0.000276044,0.000485607,0.0001263474],"domain_scores_gemma":[0.986715,0.008389331,0.003117587,0.0003262162,0.0008081386,0.0006438603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.7811228,0.001003279,0.01262332,0.0405842,0.06501449,0.0002378921,0.0001128204,0.000796872,0.002865641,0.0009112479,0.02223484,0.07249267],"study_design_scores_gemma":[0.6989952,0.06114897,0.08158578,0.00536013,0.124408,0.0004764393,0.0002423211,0.002343675,0.002415827,0.001747836,0.02117377,0.0001022098],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6260147,0.2656989,0.004628987,0.01488318,0.004940687,0.02141671,0.04556952,0.0004464262,0.01640105],"genre_scores_gemma":[0.915457,0.04218442,0.003952986,0.005119031,0.003658691,0.008161433,0.01134642,0.000117238,0.01000272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01874354,"threshold_uncertainty_score":0.06270343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1756789674265837,"score_gpt":0.4689073033172426,"score_spread":0.2932283358906588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}