{"id":"W2943897201","doi":"10.1101/634915","title":"CLN3 regulates endosomal function by modulating Rab7A activity","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Institut National de la Recherche Scientifique","funders":"","keywords":"Endosome; Batten disease; Retromer; Cell biology; Biology; Autophagy; Lysosome; Autophagosome; Endocytosis; Intracellular; Receptor; Genetics; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001119688,0.0002277484,0.0001164251,0.0001951893,0.0002218856,0.0002976379,0.0002299264,0.0002558388,0.001383416],"category_scores_gemma":[0.0001285236,0.00007150201,0.0001551446,0.0001364557,0.0002074784,0.0001080034,0.000226247,0.0002640734,0.0006029779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008017256,"about_ca_system_score_gemma":0.0001936883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0019053,"about_ca_topic_score_gemma":0.002702777,"domain_scores_codex":[0.9999217,0.000009037807,0.000006549348,0.00001710664,0.00002563012,0.00002000949],"domain_scores_gemma":[0.9999431,0.000008460251,0.00001585995,0.000006422669,0.000009516926,0.00001657017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001764397,0.00001418988,0.0004999336,0.00001718494,0.000002916629,0.0001324819,0.000007110721,0.0000866921,0.9980333,0.0001233914,0.0001533541,0.0007529219],"study_design_scores_gemma":[0.00005418345,0.00005050953,0.01089351,0.00001001212,0.000009998212,0.0004265717,0.00004232418,0.00416935,0.9808381,0.0002468054,0.003251201,0.00000750992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940884,0.000757582,0.001519645,0.0002214419,0.00004009261,0.000009941037,0.0006374311,0.0001018078,0.002623825],"genre_scores_gemma":[0.995968,0.0002045328,0.001015149,0.0000608856,0.000006273489,0.0000103334,0.0007390591,0.00004357714,0.001952154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0019053,"threshold_uncertainty_score":0.005816936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007558446446237045,"score_gpt":0.1913109446996213,"score_spread":0.1837524982533843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}