{"id":"W2943948155","doi":"10.1007/978-1-4939-9182-2_21","title":"Measurement of the Oxidative DNA Lesion 8-Oxoguanine (8-oxoG) by ELISA or by High-Performance Liquid Chromatography (HPLC) with Electrochemical Detection","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"DNA glycosylase; High-performance liquid chromatography; DNA damage; DNA; Chemistry; Reactive oxygen species; Lesion; Oxidative phosphorylation; Chromatography; Biochemistry; Molecular biology; Biology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001165022,0.001763167,0.0009820482,0.001219659,0.0004128319,0.0007806099,0.0009337238,0.001368013,0.004474612],"category_scores_gemma":[0.001355978,0.0006492331,0.0005554344,0.0009656303,0.0006580665,0.0008069682,0.0006278103,0.001855443,0.002712189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003471313,"about_ca_system_score_gemma":0.0005201081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005634865,"about_ca_topic_score_gemma":0.0008259651,"domain_scores_codex":[0.9983122,0.0004932442,0.00009549344,0.0004502924,0.0004296372,0.0002192075],"domain_scores_gemma":[0.9985031,0.0005062302,0.0002549093,0.0001695206,0.000359345,0.0002068755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002805078,0.0002106407,0.001625962,0.0001816379,0.00003385095,0.00006084595,0.00007421787,0.0001227382,0.991456,0.0002384907,0.0001965321,0.005518714],"study_design_scores_gemma":[0.00002702432,0.00063262,0.003129037,0.00002058413,0.0000416449,0.0001921694,0.00004858883,0.001302637,0.9921978,0.0003387958,0.002053278,0.00001590297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.6470892,0.008281958,0.3221778,0.0007554117,0.001114385,0.0008625838,0.004015598,0.002730062,0.01297303],"genre_scores_gemma":[0.615968,0.006884437,0.3308329,0.001303828,0.0003943227,0.002164807,0.005860427,0.0003200591,0.03627115],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.004474612,"threshold_uncertainty_score":0.01496905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00900843975929335,"score_gpt":0.2831465463379488,"score_spread":0.2741381065786554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}