{"id":"W2943980363","doi":"10.25011/cim.v42i1.32393","title":"Safety and efficacy of active and passive immunotherapy in mild-to-moderate Alzheimer’s disease: A systematic review and network meta-analysis","year":2019,"lang":"en","type":"review","venue":"Clinical and investigative medicine","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; St. Joseph’s Healthcare Hamilton; McMaster University; Programs for Assessment of Technology in Health Research Institute","funders":"","keywords":"Medicine; Meta-analysis; Randomized controlled trial; Internal medicine; Cochrane Library; Placebo; Immunotherapy; Clinical trial; MEDLINE; Disease; Physical therapy; Oncology; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03337331,0.003588479,0.02378363,0.01116418,0.0007401352,0.004296501,0.00249721,0.002523236,0.0027176],"category_scores_gemma":[0.06677181,0.001701564,0.04440278,0.008584061,0.001026299,0.002556636,0.002027596,0.001935956,0.0002489181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004041947,"about_ca_system_score_gemma":0.005074261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006079573,"about_ca_topic_score_gemma":0.01190926,"domain_scores_codex":[0.9689075,0.01927565,0.006395224,0.001995551,0.002998702,0.0004274119],"domain_scores_gemma":[0.9511017,0.03871278,0.006218962,0.001105935,0.002512516,0.0003480365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001438908,0.00002485345,0.002214007,0.297428,0.6893521,0.00007172865,0.00006603726,0.0005874935,0.000119049,0.000137897,0.0002653673,0.00829452],"study_design_scores_gemma":[0.0006534123,0.0002000863,0.001757348,0.0255254,0.9703359,0.00006755468,0.00003437769,0.0002729811,0.00008278542,0.0002265481,0.0008239932,0.00001964519],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00517184,0.991704,0.00115953,0.0002529136,0.000198915,0.0007674666,0.0004364467,0.00003173468,0.0002770567],"genre_scores_gemma":[0.2426084,0.7442686,0.006742546,0.001018257,0.0004044216,0.003636983,0.0009113782,0.00004367861,0.0003657849],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03337331,"threshold_uncertainty_score":0.176497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3763789672161888,"score_gpt":0.4692246226048892,"score_spread":0.09284565538870043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}