{"id":"W2944064358","doi":"10.1016/j.vaccine.2019.04.094","title":"Current advances in HIV vaccine preclinical studies using Macaque models","year":2019,"lang":"en","type":"review","venue":"Vaccine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Simian immunodeficiency virus; Macaque; Rhesus macaque; Virology; Human immunodeficiency virus (HIV); HIV vaccine; Immunology; Lentivirus; AIDS Vaccines; Medicine; Biology; Computational biology; Vaccine trial; Viral disease; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001396632,0.001181186,0.001835997,0.002025439,0.0002399844,0.001641014,0.0009513,0.001350343,0.005271203],"category_scores_gemma":[0.001427176,0.0003337115,0.0005466845,0.001485854,0.000517785,0.001338315,0.0007828828,0.002359045,0.002321358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006961262,"about_ca_system_score_gemma":0.001569406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001271149,"about_ca_topic_score_gemma":0.002605747,"domain_scores_codex":[0.9997465,0.00005775348,0.00003329986,0.00004164638,0.00008456624,0.00003628332],"domain_scores_gemma":[0.99925,0.0004184677,0.00008719121,0.00002394543,0.0001624602,0.00005785939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001601442,0.0001159366,0.0001544329,0.01292945,0.0000546178,0.00008878594,0.00002708255,0.0002915258,0.002993623,0.002468374,0.02375114,0.9569649],"study_design_scores_gemma":[0.00004105775,0.0002566038,0.0006572655,0.005386923,0.0002259165,0.0007274211,0.00005144362,0.0001580086,0.001545858,0.002238475,0.988686,0.00002506359],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009428769,0.9982082,0.000227938,0.0002563956,0.0002588024,0.000009527978,0.00002796116,0.00001081282,0.0009060842],"genre_scores_gemma":[0.0005184943,0.9979717,0.0003402703,0.000258089,0.000258299,0.00001236905,0.00005193881,0.000002431146,0.0005863849],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005271203,"threshold_uncertainty_score":0.01763391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2114825623515859,"score_gpt":0.4754125541819442,"score_spread":0.2639299918303583,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}