{"id":"W2944141026","doi":"10.1007/s00018-019-03115-3","title":"Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus","year":2019,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; British Columbia Knowledge Development Fund; National Institutes of Health; National Institute of General Medical Sciences; University of British Columbia","keywords":"Glycan; Biology; Bacteroides thetaiotaomicron; Bacteroides; Biochemistry; Gut flora; Curdlan; Metagenomics; Gene; Polysaccharide; Microbiology; Genetics; Bacteria; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001140435,0.0002746246,0.0001890532,0.0001244366,0.0001811231,0.000342044,0.0001280601,0.0002430884,0.0008856104],"category_scores_gemma":[0.0002448997,0.0001498027,0.0001705824,0.0001517947,0.0001713213,0.0001349117,0.0002817591,0.0002832353,0.0005334413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001708423,"about_ca_system_score_gemma":0.0001646109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001144896,"about_ca_topic_score_gemma":0.0008619559,"domain_scores_codex":[0.9998918,0.00001681661,0.000005513493,0.00002258489,0.00003181522,0.00003156475],"domain_scores_gemma":[0.9999039,0.00001214889,0.00003071723,0.000009037026,0.00001767866,0.00002652636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002297882,0.00001461232,0.002488455,0.00003206152,0.000005852773,0.0001050357,0.00002414201,0.00004374457,0.9951943,0.0001017174,0.00009586262,0.001664498],"study_design_scores_gemma":[0.00005712366,0.000550487,0.2828655,0.00002187986,0.00008435432,0.002630043,0.0003879031,0.003628684,0.7008704,0.0004587939,0.008421463,0.00002332824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975056,0.0007081878,0.0009944199,0.00008515857,0.00001472078,0.000004765371,0.0002090579,0.0000397829,0.0004383678],"genre_scores_gemma":[0.99737,0.0001963828,0.001095658,0.00004050598,0.000004822714,0.000004481305,0.0004809361,0.00001632711,0.0007909043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001144896,"threshold_uncertainty_score":0.002962649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02070047554458345,"score_gpt":0.2790485667348667,"score_spread":0.2583480911902833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}