{"id":"W2944173178","doi":"10.1039/c9md00138g","title":"Fungal natural alkaloid schizocommunin activates the aryl hydrocarbon receptor pathway","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Hospital for Sick Children; University of Ottawa","keywords":"Alkaloid; Aryl hydrocarbon receptor; Aryl; Chemistry; Hydrocarbon; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005621659,0.0002502507,0.0001377326,0.0001687934,0.0001581381,0.0002162443,0.00009129703,0.0001361803,0.000991511],"category_scores_gemma":[0.00008161336,0.00005456523,0.0001354563,0.0001647639,0.0001404856,0.000144839,0.0001845261,0.0002617667,0.0002866578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002009501,"about_ca_system_score_gemma":0.0002450076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005866986,"about_ca_topic_score_gemma":0.001225788,"domain_scores_codex":[0.9999212,0.00001509248,0.00000584566,0.00001753807,0.00002731709,0.00001307744],"domain_scores_gemma":[0.9999474,0.00001019183,0.00001193577,0.000007691596,0.00001016445,0.00001267694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009891394,0.00001745119,0.0005476961,0.0001041105,0.000005926821,0.0002164372,0.00001656777,0.0001089684,0.9918997,0.0003452213,0.00005412851,0.00658477],"study_design_scores_gemma":[0.000005742537,0.0002512644,0.005924413,0.00001266352,0.00001522077,0.001228968,0.00003828444,0.0005085561,0.9798697,0.0001705182,0.01196891,0.000005871278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9439452,0.02055062,0.01556366,0.0002293204,0.0001350436,0.0001154913,0.001423711,0.0001402422,0.01789661],"genre_scores_gemma":[0.9835972,0.006618955,0.004842788,0.00005476892,0.00001818008,0.00001956022,0.0006633751,0.00001045446,0.004174718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000991511,"threshold_uncertainty_score":0.003316998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01320217818467988,"score_gpt":0.2716307960179219,"score_spread":0.258428617833242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}