{"id":"W2944173178","doi":"10.1039/c9md00138g","title":"Fungal natural alkaloid schizocommunin activates the aryl hydrocarbon receptor pathway","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Hospital for Sick Children; University of Ottawa","keywords":"Alkaloid; Aryl hydrocarbon receptor; Aryl; Chemistry; Hydrocarbon; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004899057,0.0002880051,0.0003289299,0.0000663046,0.0002558474,0.00004861458,0.0007641782,0.0001375603,0.001229596],"category_scores_gemma":[0.00004974929,0.0001876723,0.0001636444,0.0002446791,0.0001387456,0.00008263422,0.0002837237,0.0007793884,0.002537858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004536371,"about_ca_system_score_gemma":0.00002283395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001943998,"about_ca_topic_score_gemma":0.00005031727,"domain_scores_codex":[0.9984051,0.0001610752,0.0002825943,0.0003680593,0.0002617733,0.0005214114],"domain_scores_gemma":[0.9981589,0.0004564121,0.000129805,0.001133316,0.00004882575,0.0000727355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001432375,0.001667513,0.1484939,0.0001073774,0.002295033,0.00003568267,0.03878986,0.00001048348,0.3275082,0.07086533,0.3170062,0.09178808],"study_design_scores_gemma":[0.00356893,0.0003522857,0.07073552,0.0001230019,0.00005561209,0.00005623696,0.0119624,0.0001956664,0.07390165,0.002695181,0.8351469,0.001206587],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8467197,0.003308008,0.0000031172,0.005047177,0.002748871,0.0003470055,0.00001131966,0.0001258585,0.1416889],"genre_scores_gemma":[0.9887835,0.00004547697,0.00008019728,0.00117408,0.0003335506,0.00009516603,0.00002340019,0.00004509989,0.0094195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5181407,"threshold_uncertainty_score":0.9996834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01320217818467988,"score_gpt":0.2716307960179219,"score_spread":0.258428617833242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}