{"id":"W2944192183","doi":"10.1158/1538-7445.sabcs18-pd3-10","title":"Abstract PD3-10: Higher serum PD-L1 predicts for increased overall survival to lapatinib vs trastuzumab in the phase 3 CCTG MA.31 trial","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Lapatinib; Trastuzumab; Taxane; Medicine; Internal medicine; Oncology; Metastatic breast cancer; Population; Biomarker; Breast cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001747935,0.0006339919,0.001406764,0.0001963999,0.0003478273,0.001025653,0.0004819076,0.0006619696,0.005582942],"category_scores_gemma":[0.001955596,0.0001848372,0.001341063,0.0003481099,0.0003488338,0.0004617278,0.0002716804,0.002100338,0.000511216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00119477,"about_ca_system_score_gemma":0.00136286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002359966,"about_ca_topic_score_gemma":0.007496352,"domain_scores_codex":[0.9991709,0.0004990437,0.0000447785,0.0001228907,0.00007232045,0.00009014144],"domain_scores_gemma":[0.999164,0.0002157438,0.0002197661,0.00007053748,0.00007194086,0.0002579999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8889681,0.00193418,0.02711341,0.001265355,0.00469258,0.0001597625,0.00009324304,0.001594373,0.006611915,0.0004538235,0.02116381,0.04594946],"study_design_scores_gemma":[0.7426509,0.07587967,0.147501,0.0003847128,0.007776522,0.0006069416,0.0001291534,0.007313058,0.003362812,0.002108556,0.01219149,0.00009505951],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741074,0.01113479,0.000562306,0.00224198,0.0003116207,0.001039478,0.004076724,0.0001203583,0.006405381],"genre_scores_gemma":[0.992178,0.0008806688,0.0003263113,0.0008302999,0.0002379811,0.0007752972,0.002852351,0.00001843407,0.001900547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005582942,"threshold_uncertainty_score":0.01867676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1175320752193414,"score_gpt":0.4462267214256554,"score_spread":0.328694646206314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}