{"id":"W2944239560","doi":"10.1210/js.2019-sat-347","title":"SAT-347 Unfolding Generates an Active CYP11A1 for Mitochondrial Integration and Activity","year":2019,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Translocase; Translocase of the inner membrane; Translocase of the outer membrane; Protein targeting; Inner mitochondrial membrane; Inner membrane; Cell biology; Mitochondrial carrier; Mitochondrion; Mitochondrial membrane transport protein; ATP–ADP translocase; Biology; Protein subunit; Chemistry; Biochemistry; Membrane protein; Bacterial outer membrane; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009114624,0.000073674,0.0000980383,0.000008154211,0.00008974736,0.00003004127,0.0001214488,0.0000409388,0.000006026607],"category_scores_gemma":[0.00003550784,0.00004815822,0.0001854391,0.00003591408,0.00002921744,0.00001853566,0.00003637087,0.0000998002,2.839854e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002741248,"about_ca_system_score_gemma":0.00006448244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005144648,"about_ca_topic_score_gemma":0.000007032479,"domain_scores_codex":[0.9995627,0.00003466195,0.0001191506,0.0001083618,0.00007975824,0.00009537583],"domain_scores_gemma":[0.9994769,0.00001428818,0.0001861703,0.000149082,0.0001391305,0.00003449603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001118351,0.00002842515,0.0004887521,0.000005799998,0.00006233288,5.591321e-8,0.0001146081,0.0001331519,0.9916416,0.00004669103,0.002103413,0.005263329],"study_design_scores_gemma":[0.0009402085,0.0002868308,0.00374692,0.00001233408,0.00003947528,0.00003120867,0.0005162759,0.0008462436,0.9819322,0.0001426171,0.01142069,0.00008502342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942819,0.0001855434,0.004239797,0.000602079,0.0004832559,0.0001530136,0.00001490133,0.000001587756,0.00003785782],"genre_scores_gemma":[0.9960949,0.0001814889,0.002430962,0.0001309495,0.0007291572,0.000006519263,0.000006831503,0.000009163163,0.00041007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009709436,"threshold_uncertainty_score":0.1963835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01087651787734461,"score_gpt":0.2773336777730644,"score_spread":0.2664571598957198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}