{"id":"W2944239560","doi":"10.1210/js.2019-sat-347","title":"SAT-347 Unfolding Generates an Active CYP11A1 for Mitochondrial Integration and Activity","year":2019,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Translocase; Translocase of the inner membrane; Translocase of the outer membrane; Protein targeting; Inner mitochondrial membrane; Inner membrane; Cell biology; Mitochondrial carrier; Mitochondrion; Mitochondrial membrane transport protein; ATP–ADP translocase; Biology; Protein subunit; Chemistry; Biochemistry; Membrane protein; Bacterial outer membrane; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001491441,0.0003269506,0.0001587159,0.0002289865,0.0002428959,0.0002635284,0.0001920699,0.0002634605,0.005337265],"category_scores_gemma":[0.0001722771,0.0001652566,0.0002960161,0.0002316674,0.0002150224,0.0001253734,0.000225603,0.0005811753,0.001982005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005401187,"about_ca_system_score_gemma":0.0002702407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007865559,"about_ca_topic_score_gemma":0.001397868,"domain_scores_codex":[0.9998672,0.0000240944,0.000008991306,0.00003152372,0.00003968701,0.00002848996],"domain_scores_gemma":[0.9998305,0.0000285997,0.00003694552,0.00003220762,0.00001954155,0.00005214613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005992759,0.00001707848,0.0002580999,0.00001237782,0.000004600453,0.00005727287,0.000007590176,0.00004807439,0.9982435,0.0002259746,0.0000904764,0.0009749483],"study_design_scores_gemma":[0.00001152157,0.00007001336,0.003671166,0.00000245652,0.00001034271,0.0001890941,0.00001667977,0.0007835478,0.9883351,0.00009165132,0.006812774,0.000005550593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821388,0.0006435505,0.009928882,0.000331327,0.0001239318,0.00005952099,0.001732222,0.0003710853,0.004670739],"genre_scores_gemma":[0.9865317,0.0001695672,0.002518436,0.00009000358,0.00001223764,0.00002668449,0.002795994,0.0001434271,0.007712039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005337265,"threshold_uncertainty_score":0.01785493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01087651787734461,"score_gpt":0.2773336777730644,"score_spread":0.2664571598957198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}