{"id":"W2944281527","doi":"10.1016/j.chom.2019.04.009","title":"Carving a Niche for Antibacterial α-Defensins when Craving","year":2019,"lang":"en","type":"letter","venue":"Cell Host & Microbe","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Defensin; Microbiology; Gastrointestinal tract; Staphylococcus aureus; Host (biology); Regulator; PI3K/AKT/mTOR pathway; Bacteria; Cell biology; Antimicrobial; Genetics; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002013172,0.0008166468,0.001189804,0.000230738,0.0004019459,0.0001811134,0.0007235261,0.002420967,0.001129236],"category_scores_gemma":[0.0000477883,0.0008051057,0.0006963598,0.0000714215,0.0003251945,0.0001673113,0.0004101327,0.002050059,0.001767436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001315806,"about_ca_system_score_gemma":0.000248454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003671826,"about_ca_topic_score_gemma":0.00002457545,"domain_scores_codex":[0.9968405,0.0001799712,0.0006138978,0.001036493,0.00004899689,0.001280169],"domain_scores_gemma":[0.9979816,0.0004716321,0.0005394035,0.0008215124,0.000165456,0.00002037757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005103053,0.00002725243,0.00003950102,0.0003276525,0.0001233083,0.00001598394,0.0002478847,2.798494e-7,0.4861779,0.000002902026,0.5128831,0.0001031899],"study_design_scores_gemma":[0.001132761,0.0001342517,0.00003193186,0.0002680979,0.0002311276,0.00008664263,0.00008422761,4.726574e-7,0.2235945,0.0000197927,0.7736613,0.0007549732],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.437867,0.02105632,0.00302885,0.4065415,0.07608791,0.01168716,0.01647891,0.001685266,0.02556703],"genre_scores_gemma":[0.03150288,0.0003681639,0.001783599,0.5927518,0.008462958,0.00007117147,0.01072798,0.0006792156,0.3536522],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4063641,"threshold_uncertainty_score":0.9997839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353974010108029,"score_gpt":0.2135563117537564,"score_spread":0.2000165716526761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}