{"id":"W2944352931","doi":"10.1016/j.cgh.2019.04.059","title":"Tofacitinib Treatment Is Associated With Modest and Reversible Increases in Serum Lipids in Patients With Ulcerative Colitis","year":2019,"lang":"en","type":"review","venue":"Clinical Gastroenterology and Hepatology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"Pfizer","keywords":"Tofacitinib; Medicine; Ulcerative colitis; Placebo; Janus kinase inhibitor; Internal medicine; Gastroenterology; Adverse effect; Lipid profile; Cholesterol; Rheumatoid arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001366271,0.0003837814,0.0007089069,0.0006339657,0.0003495291,0.0006632775,0.0002070568,0.0004524612,0.001123997],"category_scores_gemma":[0.003769007,0.0002428114,0.0008447309,0.0009390143,0.0002706982,0.0003858717,0.0003332552,0.0009334414,0.0001255276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003524287,"about_ca_system_score_gemma":0.0002394781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005749412,"about_ca_topic_score_gemma":0.001216493,"domain_scores_codex":[0.998679,0.0004597137,0.0001976598,0.0002018849,0.0003200457,0.0001417701],"domain_scores_gemma":[0.9944847,0.001087297,0.003658225,0.0001944636,0.0002112407,0.0003639201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003838851,0.0001398684,0.9787148,0.00009164515,0.0003688271,0.0004060621,0.00004716147,0.0001587122,0.002199367,0.00002576071,0.0001853837,0.01382348],"study_design_scores_gemma":[0.00006734064,0.0004431891,0.9981237,0.00001198149,0.0001161742,0.0005631871,0.00003202577,0.0001570803,0.0001960626,0.00002980311,0.0002541422,0.000005362854],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9945354,0.004154775,0.0001427104,0.0001673783,0.00001621071,0.00001886241,0.0001914404,0.00001410731,0.0007590769],"genre_scores_gemma":[0.9991789,0.0003811503,0.0001177141,0.00005912067,0.00002741242,0.00000582371,0.0001512384,0.000002014191,0.00007659523],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001366271,"threshold_uncertainty_score":0.007225633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02897282335647547,"score_gpt":0.3081179435170247,"score_spread":0.2791451201605493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}