{"id":"W2944399404","doi":"10.1111/acel.12956","title":"Are skin senescence and immunosenescence linked within individuals?","year":2019,"lang":"en","type":"article","venue":"Aging Cell","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences North","funders":"Centre for Medical Systems Biology; Novo Nordisk; Novo Nordisk Fonden; Deutsche Forschungsgemeinschaft; European Commission; Unilever","keywords":"Immunosenescence; Biology; Senescence; Computational biology; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003186321,0.0002762645,0.0004306021,0.0001554596,0.0001130286,0.00006652265,0.0001918068,0.0001355542,0.0001388044],"category_scores_gemma":[0.0000648786,0.0002489884,0.00007253379,0.0003177508,0.0001292863,0.0001788795,0.0001218383,0.0003950804,0.0004599535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004298382,"about_ca_system_score_gemma":0.00008883014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00020871,"about_ca_topic_score_gemma":0.00001561631,"domain_scores_codex":[0.9981971,0.00005985987,0.0003464346,0.0005689968,0.0003872164,0.0004403819],"domain_scores_gemma":[0.998722,0.0001125197,0.0002634985,0.000593143,0.00009654569,0.0002123225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004087137,0.000120165,0.9045923,0.000438195,0.0000265825,0.0001170399,0.002076238,0.000006409993,0.08890817,0.00004586079,0.0003171162,0.003311084],"study_design_scores_gemma":[0.001805011,0.0001244568,0.9362566,0.0007326099,0.00007260347,0.0001678897,0.001769873,0.0004248481,0.05470161,0.00005152062,0.003434506,0.0004584069],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954722,0.001600221,0.00005289158,0.000571624,0.0004307034,0.0004055324,0.000005939837,0.0001547102,0.001306185],"genre_scores_gemma":[0.9930238,0.0002433305,0.001419811,0.001394673,0.0001313682,0.000006565055,0.00001373511,0.00004184393,0.00372486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03420655,"threshold_uncertainty_score":0.9999962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01085932752585423,"score_gpt":0.2389963769867111,"score_spread":0.2281370494608569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}