{"id":"W2944489822","doi":"10.1016/j.eururo.2019.04.036","title":"Molecular Subtyping of Clinically Localized Urothelial Carcinoma Reveals Lower Rates of Pathological Upstaging at Radical Cystectomy Among Luminal Tumors","year":2019,"lang":"en","type":"article","venue":"European Urology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"Genome British Columbia","funders":"","keywords":"Medicine; Cystectomy; Pathological; Urology; Logistic regression; Subtyping; Bladder cancer; Stage (stratigraphy); Oncology; Internal medicine; Retrospective cohort study; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008114111,0.0002770817,0.0009107807,0.0001291083,0.00003823143,0.000005147285,0.0002450996,0.0001355033,0.0007006714],"category_scores_gemma":[0.0002725909,0.0002218619,0.0003152324,0.0001621336,0.0006162407,0.00003495842,0.0002103702,0.0003411575,0.0001305891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004481773,"about_ca_system_score_gemma":0.00009411661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003240879,"about_ca_topic_score_gemma":0.000001292038,"domain_scores_codex":[0.9968454,0.0008340749,0.00103151,0.0005567332,0.000298802,0.0004334608],"domain_scores_gemma":[0.9985033,0.0002205915,0.0004009993,0.0005611797,0.0001196692,0.000194215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00491786,0.0003393695,0.9070775,0.0001295096,0.0001409866,0.002323058,0.0002636466,0.00004102337,0.08409132,0.00009498717,0.000189966,0.0003907638],"study_design_scores_gemma":[0.01448127,0.008760265,0.9533703,0.0001969395,0.0005009258,0.0008318629,0.00006774825,0.0002465692,0.01850818,0.00009514635,0.002528144,0.0004126915],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826011,0.0003684261,0.0002402448,0.0002040065,0.0002623181,0.000605369,0.00002390128,0.00004834279,0.0156463],"genre_scores_gemma":[0.9977108,0.00001477712,0.0003645318,0.001143068,0.000146736,0.000007832128,0.00002358313,0.0000676568,0.0005210224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06558313,"threshold_uncertainty_score":0.9047267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01567969441747168,"score_gpt":0.2775872557985292,"score_spread":0.2619075613810575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}