{"id":"W2944495935","doi":"10.3390/antiox8050126","title":"H2O2 Metabolism in Normal Thyroid Cells and in Thyroid Tumorigenesis: Focus on NADPH Oxidases","year":2019,"lang":"en","type":"review","venue":"Antioxidants","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"NOX4; NADPH oxidase; NOX1; Reactive oxygen species; Thyroid; Chemistry; Biochemistry; Carcinogenesis; Enzyme; Oxidase test; Internal medicine; Endocrinology; Biology; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002618567,0.000855809,0.003105226,0.0009299117,0.00005616924,0.00004807154,0.0002322323,0.0004417682,0.00005158973],"category_scores_gemma":[0.00006560317,0.0006598784,0.0004337625,0.000684039,0.00007845659,0.0001617761,0.0001235545,0.0005839286,0.0005116818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001371144,"about_ca_system_score_gemma":0.0003464399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005986093,"about_ca_topic_score_gemma":0.0002597603,"domain_scores_codex":[0.996639,0.0002026627,0.0009746321,0.0009733446,0.00043953,0.0007708364],"domain_scores_gemma":[0.9985006,0.0001783018,0.0003484505,0.0007139564,0.00004976122,0.0002088856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000644554,0.004354807,0.00532481,0.01698851,0.0009535759,0.003213133,0.0003392688,0.000003283469,0.0008186817,0.0003631446,0.001972701,0.9650235],"study_design_scores_gemma":[0.02639697,0.002456117,0.09341516,0.05817926,0.005941997,0.0007484831,0.0003730013,0.00001286204,0.001837233,0.0004204084,0.8063728,0.003845697],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06700237,0.9285248,6.456996e-7,0.00004474905,0.000358718,0.001791041,0.0001461236,0.00004505782,0.00208649],"genre_scores_gemma":[0.03730064,0.9608378,0.00006359216,0.0001638615,0.0001279401,0.0001371016,0.00009257946,0.0001275323,0.001148904],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9611778,"threshold_uncertainty_score":0.9995853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02983354015347072,"score_gpt":0.3042755458783187,"score_spread":0.274442005724848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}