{"id":"W2944546179","doi":"10.1038/s41568-019-0145-5","title":"Going to extremes: determinants of extraordinary response and survival in patients with cancer","year":2019,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; BC Cancer Agency","funders":"National Cancer Institute","keywords":"Medicine; Disease; Cancer; Outcome (game theory); Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008802422,0.000665618,0.001868958,0.001031583,0.0002086904,0.001385054,0.0008313943,0.001447565,0.00251861],"category_scores_gemma":[0.002490086,0.0002361948,0.000651866,0.001497363,0.0007069471,0.001154465,0.000755086,0.002745098,0.001092016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000769583,"about_ca_system_score_gemma":0.0009220941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00088414,"about_ca_topic_score_gemma":0.001812326,"domain_scores_codex":[0.9996309,0.0001196149,0.00004974617,0.00006516935,0.00009573136,0.00003890486],"domain_scores_gemma":[0.9989706,0.0006835213,0.0001516608,0.00001658565,0.0001287424,0.00004880149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001934186,0.00004577834,0.001519182,0.009816123,0.0002065867,0.0001004115,0.0000605965,0.0003418588,0.0003766983,0.005725432,0.04385152,0.9377623],"study_design_scores_gemma":[0.00007519672,0.0002346117,0.009980039,0.0160922,0.0005466243,0.001806228,0.0002159045,0.0002886111,0.00036083,0.01734317,0.9529867,0.00006992587],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007629781,0.9987136,0.00004085151,0.0007343695,0.0001353066,0.000001310873,0.00001605682,0.000002444386,0.0002797632],"genre_scores_gemma":[0.001042885,0.9978967,0.00005445478,0.00046815,0.0003517857,0.000005573473,0.0000246041,8.863066e-7,0.0001548926],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00251861,"threshold_uncertainty_score":0.008425653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04801579366690634,"score_gpt":0.3960051989968452,"score_spread":0.3479894053299388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}