{"id":"W2944594140","doi":"10.1111/ijlh.13011","title":"Sensitive and accurate identification of PNH clones based on ICCS/ESCCA PNH Consensus Guidelines—A summary","year":2019,"lang":"en","type":"review","venue":"International Journal of Laboratory Hematology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Paroxysmal nocturnal hemoglobinuria; CD59; Identification (biology); Computational biology; Biology; Medicine; Immunology; Complement system; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00678324,0.0008779622,0.001741673,0.003908408,0.0003760615,0.001496881,0.002649673,0.002227303,0.002384324],"category_scores_gemma":[0.006997017,0.0004004406,0.001146234,0.001899452,0.0007131273,0.001595653,0.001018421,0.002414099,0.002877753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001350201,"about_ca_system_score_gemma":0.004223889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002239739,"about_ca_topic_score_gemma":0.002338572,"domain_scores_codex":[0.9972416,0.0006399169,0.0007608695,0.0002718353,0.0009110062,0.0001747788],"domain_scores_gemma":[0.9944331,0.0016639,0.0004452731,0.0001369001,0.003118658,0.0002021127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001157257,0.0001049857,0.001334709,0.01294701,0.0001092145,0.0003527337,0.0001120727,0.0003750589,0.002243196,0.005233174,0.1050418,0.8720304],"study_design_scores_gemma":[0.00002203203,0.0001099915,0.00215074,0.008546181,0.0001930103,0.001424343,0.0001142051,0.0001848811,0.002012684,0.001996191,0.983209,0.00003673898],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009532489,0.9713196,0.005421179,0.01028809,0.002844364,0.0002086005,0.0005618719,0.000131008,0.008272068],"genre_scores_gemma":[0.006474512,0.9624656,0.01396598,0.007552969,0.001965757,0.0004045464,0.002519429,0.00005425435,0.004596876],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00678324,"threshold_uncertainty_score":0.03587365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0716949799311318,"score_gpt":0.3929313859146206,"score_spread":0.3212364059834888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}