{"id":"W2944594140","doi":"10.1111/ijlh.13011","title":"Sensitive and accurate identification of PNH clones based on ICCS/ESCCA PNH Consensus Guidelines—A summary","year":2019,"lang":"en","type":"review","venue":"International Journal of Laboratory Hematology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Paroxysmal nocturnal hemoglobinuria; CD59; Identification (biology); Computational biology; Biology; Medicine; Immunology; Complement system; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009476308,0.0004010132,0.001982623,0.0008363543,0.00005861289,0.00003298876,0.0006013386,0.0004334042,0.0001544231],"category_scores_gemma":[0.001167634,0.0003322967,0.0003918676,0.0001807314,0.0003357338,0.00008355208,0.0001267734,0.0004491007,0.0001321141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001355594,"about_ca_system_score_gemma":0.001322577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007999096,"about_ca_topic_score_gemma":0.000005229811,"domain_scores_codex":[0.9953408,0.001108488,0.002760718,0.0003616127,0.0002094523,0.0002189138],"domain_scores_gemma":[0.9902827,0.001722559,0.004389883,0.0003655465,0.003193307,0.00004598255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.008666104,0.005120224,0.009791068,0.06883132,0.04534316,0.006601915,0.0009445788,0.0006579953,0.01985999,0.04539243,0.4560522,0.332739],"study_design_scores_gemma":[0.002142794,0.0002949145,0.0001928173,0.01581288,0.001367498,0.002740996,0.0001851478,0.00003119234,0.002391066,0.00008627132,0.9742604,0.0004939727],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00252026,0.9893677,0.0001350674,0.0004794154,0.005064129,0.0004973432,0.001849146,0.0000186273,0.00006830153],"genre_scores_gemma":[0.0547934,0.9431664,0.0001878167,0.0004608962,0.0003297596,0.00003135761,0.00068213,0.00008682364,0.0002614665],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5182082,"threshold_uncertainty_score":0.9999129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0716949799311318,"score_gpt":0.3929313859146206,"score_spread":0.3212364059834888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}