{"id":"W2944604647","doi":"10.1210/js.2019-sun-482","title":"SUN-482 Nitric Oxide Induces Spexin (Spx), Galanin Receptor 2 (GalR2), and Galanin Receptor 3 (GalR3) mRNA Independently of the cGMP/PKG Pathway and Enhances C/EBP-β Binding to the Spx 5’ Regulatory Region","year":2019,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Galanin; Biology; Receptor; Nitric oxide; Internal medicine; Endocrinology; cGMP-dependent protein kinase; Sodium nitroprusside; Neuropeptide; Signal transduction; Cell biology; Protein kinase A; Kinase; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008472754,0.0002526459,0.0002795844,0.0001433036,0.00009961548,0.0001737279,0.0001126926,0.0002184542,0.001861181],"category_scores_gemma":[0.00007203405,0.0001237535,0.0003652923,0.00008960326,0.0002333694,0.0001471986,0.0001475489,0.0005608706,0.0002640351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001585009,"about_ca_system_score_gemma":0.0001273011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002725597,"about_ca_topic_score_gemma":0.0005244531,"domain_scores_codex":[0.9998692,0.00001492749,0.00001081703,0.00003516716,0.00002900205,0.00004086521],"domain_scores_gemma":[0.9999239,0.00001309045,0.00002034883,0.000009377915,0.000004777881,0.00002840123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002521142,0.00003910152,0.0001643396,0.00002340512,0.00000332999,0.00004411607,0.00000987228,0.00002109029,0.9988145,0.00002856089,0.00003020641,0.0005694121],"study_design_scores_gemma":[0.0000378187,0.0009760321,0.01250671,0.00000479578,0.00001207801,0.000185852,0.00005978657,0.0007789033,0.9843726,0.00005127705,0.001008951,0.000005161891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977558,0.0004869392,0.0005943264,0.00006130905,0.00004492213,0.00001146623,0.0001867758,0.00004252193,0.0008159793],"genre_scores_gemma":[0.9953999,0.0003966726,0.0007051672,0.00008371544,0.00001571111,0.00004158127,0.0004503893,0.00001324412,0.002893776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001861181,"threshold_uncertainty_score":0.006226301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01670509044694811,"score_gpt":0.2338264005503355,"score_spread":0.2171213101033874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}